Rapid MHC-II antigen presentation of HIV type 1 by human dendritic cells

HIV-1 is taken up by dendritic cells (DC) and degradation is detectable within a few hours. Little is known about how rapidly HIV-peptide-loaded MHC-II complexes appear on the surface of DC, however. A key impediment to the detailed understanding of MHC-II antigen presentation of HIV-1 has been the...

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Veröffentlicht in:	AIDS research and human retroviruses 2007-06, Vol.23 (6), p.812-816
Hauptverfasser:	JONES, Leola, MCDONALD, David, CANADAY, David H
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Antigen Presentation Biological and medical sciences Cells, Cultured Dendritic cells Dendritic Cells - immunology Dendritic Cells - virology Fundamental and applied biological sciences. Psychology Health aspects Histocompatibility Antigens Class II - immunology HIV infection HIV Reverse Transcriptase - immunology HIV-1 - immunology Human immunodeficiency virus 1 Human viral diseases Humans Immune recognition Infectious diseases Major histocompatibility complex Medical sciences Microbiology Miscellaneous Physiological aspects Retrovirus Viral diseases Virology
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