Ionic effects on viral DNA packaging and portal motor function in bacteriophage phi 29

In many viruses, DNA is confined at such high density that its bending rigidity and electrostatic self-repulsion present a strong energy barrier in viral assembly. Therefore, a powerful molecular motor is needed to package the DNA into the viral capsid. Here, we investigate the role of electrostatic...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2007-07, Vol.104 (27), p.11245-11250
Hauptverfasser:	Fuller, Derek N, Rickgauer, John Peter, Jardine, Paul J, Grimes, Shelley, Anderson, Dwight L, Smith, Douglas E
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus Phages - chemistry Bacillus Phages - genetics Bacillus Phages - physiology Bacteria Capsid - chemistry Capsid - physiology Cations, Divalent - chemistry Cations, Monovalent - chemistry Cobalt - chemistry Cobalt - physiology DNA, Viral - chemistry DNA, Viral - physiology Magnesium - chemistry Magnesium - physiology Optical Tweezers Predictive Value of Tests Sodium - chemistry Sodium - physiology Static Electricity Virus Assembly - physiology
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