A simple spectrophotometric method for the determination of β-blockers in dosage forms

A simple, extraction-free spectrophotometric method is proposed for the analysis of some β-blockers, namely atenolol, timolol and nadolol. The method is based on the interaction of the drugs in chloroform with 0.1% chloroformic solutions of acidic sulphophthalein dyes to form stable, yellow-coloured...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2006-01, Vol.40 (1), p.151-156
1. Verfasser:	Al-Ghannam, S.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - analysis Adrenergic beta-Antagonists - chemistry Analysis Analytical, structural and metabolic biochemistry Atenolol Atenolol - analysis Biological and medical sciences Bromcresol Purple - pharmacology Bromphenol Blue - pharmacology Bromthymol Blue - pharmacology Chemistry Techniques, Analytical - methods Chemistry, Pharmaceutical - methods Chloroform - chemistry Coloring Agents - analysis Coloring Agents - pharmacology Dosage forms Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology General pharmacology Ions Kinetics Medical sciences Models, Chemical Nadolol Nadolol - analysis Pharmacology. Drug treatments Spectrophotometry, Ultraviolet - methods Sulphophthalein dyes Tablets Thermodynamics Timolol Timolol - analysis β-Blockers
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