Randomized controlled trial of percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic back pain : Lack of effect from a 90-second 70 C lesion
A prospective double-blind randomized trial in 28 patients. To assess the clinical effect of percutaneous intradiscal radiofrequency thermocoagulation for reducing pain, functional disability, and physical impairment in patients with chronic discogenic low back pain. Chronic discogenic low back pain...
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| Veröffentlicht in: | Spine (Philadelphia, Pa. 1976) Pa. 1976), 2001-02, Vol.26 (3), p.287-292 |
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| container_title | Spine (Philadelphia, Pa. 1976) |
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| creator | BARENDSE, Gerard A. M VAN DEN BERG, Suzanne G. M KESSELS, Alfons H. F WEBER, Wim E. J VAN KLEEF, Maarten |
| description | A prospective double-blind randomized trial in 28 patients.
To assess the clinical effect of percutaneous intradiscal radiofrequency thermocoagulation for reducing pain, functional disability, and physical impairment in patients with chronic discogenic low back pain.
Chronic discogenic low back pain is a challenging problem in western countries. A treatment option is radiofrequency heating of the affected disc. Its clinical efficacy has never been formally tested in a controlled trial.
Twenty-eight patients with a history of at least 1 year of chronic low back pain were selected on the basis of a diagnostic anesthetization of the lower intervertebral discs. Only patients with one putative painful level were selected and randomly assigned to one of two treatment groups. Each patient in the radiofrequency treatment group (n = 13) received a 90-second 70 C lesion of the intervertebral disc. Patients in the control group (n = 15) underwent the same procedure, but without use of radiofrequency current. Both the treating physician and the patients were blinded to the group assignment. Before treatment, physical impairment, rating of pain, the degree of disability, and quality of life were assessed by a blinded investigator.
Eight weeks after treatment, there was one success in the radiofrequency group (n = 13) and two in the control group (n = 15). The adjusted and unadjusted odds ratio was 0.5 and 1.1, respectively (not significant). Also, visual analog scores for pain, global perceived effect, and the Oswestry disability scale showed no differences between the two groups.
Percutaneous intradiscal radiofrequency thermocoagulation (90 seconds, 70 C) is not effective in reducing chronic discogenic low back pain. |
| doi_str_mv | 10.1097/00007632-200102010-00014 |
| format | Article |
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To assess the clinical effect of percutaneous intradiscal radiofrequency thermocoagulation for reducing pain, functional disability, and physical impairment in patients with chronic discogenic low back pain.
Chronic discogenic low back pain is a challenging problem in western countries. A treatment option is radiofrequency heating of the affected disc. Its clinical efficacy has never been formally tested in a controlled trial.
Twenty-eight patients with a history of at least 1 year of chronic low back pain were selected on the basis of a diagnostic anesthetization of the lower intervertebral discs. Only patients with one putative painful level were selected and randomly assigned to one of two treatment groups. Each patient in the radiofrequency treatment group (n = 13) received a 90-second 70 C lesion of the intervertebral disc. Patients in the control group (n = 15) underwent the same procedure, but without use of radiofrequency current. Both the treating physician and the patients were blinded to the group assignment. Before treatment, physical impairment, rating of pain, the degree of disability, and quality of life were assessed by a blinded investigator.
Eight weeks after treatment, there was one success in the radiofrequency group (n = 13) and two in the control group (n = 15). The adjusted and unadjusted odds ratio was 0.5 and 1.1, respectively (not significant). Also, visual analog scores for pain, global perceived effect, and the Oswestry disability scale showed no differences between the two groups.
Percutaneous intradiscal radiofrequency thermocoagulation (90 seconds, 70 C) is not effective in reducing chronic discogenic low back pain.</description><identifier>ISSN: 0362-2436</identifier><identifier>EISSN: 1528-1159</identifier><identifier>DOI: 10.1097/00007632-200102010-00014</identifier><identifier>PMID: 11224865</identifier><identifier>CODEN: SPINDD</identifier><language>eng</language><publisher>Philadelphia, PA: Lippincott</publisher><subject>Adult ; Biological and medical sciences ; Catheter Ablation - adverse effects ; Catheter Ablation - instrumentation ; Catheter Ablation - methods ; Denervation - instrumentation ; Denervation - methods ; Diseases of the osteoarticular system. Orthopedic treatment ; Diskectomy, Percutaneous - adverse effects ; Diskectomy, Percutaneous - instrumentation ; Diskectomy, Percutaneous - methods ; Female ; Humans ; Intervertebral Disc - innervation ; Intervertebral Disc - pathology ; Intervertebral Disc - surgery ; Intervertebral Disc Displacement - complications ; Intervertebral Disc Displacement - pathology ; Intervertebral Disc Displacement - surgery ; Low Back Pain - etiology ; Low Back Pain - pathology ; Low Back Pain - surgery ; Male ; Medical sciences ; Middle Aged ; Nociceptors - cytology ; Nociceptors - physiology ; Nociceptors - surgery ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Spinal Nerves - cytology ; Spinal Nerves - physiology ; Spinal Nerves - surgery ; Treatment Outcome</subject><ispartof>Spine (Philadelphia, Pa. 1976), 2001-02, Vol.26 (3), p.287-292</ispartof><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c338t-ace1a252352c3c7adc5e5ba61fab939b73788dec4f188ac87445b984d09cd05f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=909206$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11224865$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BARENDSE, Gerard A. M</creatorcontrib><creatorcontrib>VAN DEN BERG, Suzanne G. M</creatorcontrib><creatorcontrib>KESSELS, Alfons H. F</creatorcontrib><creatorcontrib>WEBER, Wim E. J</creatorcontrib><creatorcontrib>VAN KLEEF, Maarten</creatorcontrib><title>Randomized controlled trial of percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic back pain : Lack of effect from a 90-second 70 C lesion</title><title>Spine (Philadelphia, Pa. 1976)</title><addtitle>Spine (Phila Pa 1976)</addtitle><description>A prospective double-blind randomized trial in 28 patients.
To assess the clinical effect of percutaneous intradiscal radiofrequency thermocoagulation for reducing pain, functional disability, and physical impairment in patients with chronic discogenic low back pain.
Chronic discogenic low back pain is a challenging problem in western countries. A treatment option is radiofrequency heating of the affected disc. Its clinical efficacy has never been formally tested in a controlled trial.
Twenty-eight patients with a history of at least 1 year of chronic low back pain were selected on the basis of a diagnostic anesthetization of the lower intervertebral discs. Only patients with one putative painful level were selected and randomly assigned to one of two treatment groups. Each patient in the radiofrequency treatment group (n = 13) received a 90-second 70 C lesion of the intervertebral disc. Patients in the control group (n = 15) underwent the same procedure, but without use of radiofrequency current. Both the treating physician and the patients were blinded to the group assignment. Before treatment, physical impairment, rating of pain, the degree of disability, and quality of life were assessed by a blinded investigator.
Eight weeks after treatment, there was one success in the radiofrequency group (n = 13) and two in the control group (n = 15). The adjusted and unadjusted odds ratio was 0.5 and 1.1, respectively (not significant). Also, visual analog scores for pain, global perceived effect, and the Oswestry disability scale showed no differences between the two groups.
Percutaneous intradiscal radiofrequency thermocoagulation (90 seconds, 70 C) is not effective in reducing chronic discogenic low back pain.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Catheter Ablation - adverse effects</subject><subject>Catheter Ablation - instrumentation</subject><subject>Catheter Ablation - methods</subject><subject>Denervation - instrumentation</subject><subject>Denervation - methods</subject><subject>Diseases of the osteoarticular system. Orthopedic treatment</subject><subject>Diskectomy, Percutaneous - adverse effects</subject><subject>Diskectomy, Percutaneous - instrumentation</subject><subject>Diskectomy, Percutaneous - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Intervertebral Disc - innervation</subject><subject>Intervertebral Disc - pathology</subject><subject>Intervertebral Disc - surgery</subject><subject>Intervertebral Disc Displacement - complications</subject><subject>Intervertebral Disc Displacement - pathology</subject><subject>Intervertebral Disc Displacement - surgery</subject><subject>Low Back Pain - etiology</subject><subject>Low Back Pain - pathology</subject><subject>Low Back Pain - surgery</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nociceptors - cytology</subject><subject>Nociceptors - physiology</subject><subject>Nociceptors - surgery</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Spinal Nerves - cytology</subject><subject>Spinal Nerves - physiology</subject><subject>Spinal Nerves - surgery</subject><subject>Treatment Outcome</subject><issn>0362-2436</issn><issn>1528-1159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkduK1TAUhoMoznbGV5CA4F01h6ZJvJONJ9ggDM51WV1JZqJts03ai_GF5jVN3dsxEPKT9a1D8hNCOXvLmdXvWF26k6IRjHEm6m7qDW-fkB1XwjScK_uU7JjsKtLK7oK8KOVHRTrJ7XNywbkQrenUjjxcw-zSFH97RzHNS07jWOWSI4w0BXr0GdcFZp_WQmONg4sFa2wTKWT_a_Uz3tPlzucpYYLbdYQlppmGlCne5TRHpFtOuvWbHAB_0iPEmb6nh03XJj4EjwsNOU0UqGVN8XUWRzWjezr6UstdkWcBxuJfns9LcvPp4_f9l-bw7fPX_YdDg1KapQH0HIQSUgmUqMGh8mqAjgcYrLSDltoY57EN3BhAo9tWDda0jll0TAV5Sd6c6h5zqk8rSz_V2f04nr6g16zTVnemguYEYk6lZB_6Y44T5Pues34zqf9nUv9oUv_XpJr66txjHSbv_ieeXanA6zMA21-HDDPG8shZZkV18g-OQJx0</recordid><startdate>20010201</startdate><enddate>20010201</enddate><creator>BARENDSE, Gerard A. 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J ; VAN KLEEF, Maarten</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-ace1a252352c3c7adc5e5ba61fab939b73788dec4f188ac87445b984d09cd05f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Catheter Ablation - adverse effects</topic><topic>Catheter Ablation - instrumentation</topic><topic>Catheter Ablation - methods</topic><topic>Denervation - instrumentation</topic><topic>Denervation - methods</topic><topic>Diseases of the osteoarticular system. Orthopedic treatment</topic><topic>Diskectomy, Percutaneous - adverse effects</topic><topic>Diskectomy, Percutaneous - instrumentation</topic><topic>Diskectomy, Percutaneous - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Intervertebral Disc - innervation</topic><topic>Intervertebral Disc - pathology</topic><topic>Intervertebral Disc - surgery</topic><topic>Intervertebral Disc Displacement - complications</topic><topic>Intervertebral Disc Displacement - pathology</topic><topic>Intervertebral Disc Displacement - surgery</topic><topic>Low Back Pain - etiology</topic><topic>Low Back Pain - pathology</topic><topic>Low Back Pain - surgery</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nociceptors - cytology</topic><topic>Nociceptors - physiology</topic><topic>Nociceptors - surgery</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Spinal Nerves - cytology</topic><topic>Spinal Nerves - physiology</topic><topic>Spinal Nerves - surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BARENDSE, Gerard A. M</creatorcontrib><creatorcontrib>VAN DEN BERG, Suzanne G. M</creatorcontrib><creatorcontrib>KESSELS, Alfons H. F</creatorcontrib><creatorcontrib>WEBER, Wim E. 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J</au><au>VAN KLEEF, Maarten</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Randomized controlled trial of percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic back pain : Lack of effect from a 90-second 70 C lesion</atitle><jtitle>Spine (Philadelphia, Pa. 1976)</jtitle><addtitle>Spine (Phila Pa 1976)</addtitle><date>2001-02-01</date><risdate>2001</risdate><volume>26</volume><issue>3</issue><spage>287</spage><epage>292</epage><pages>287-292</pages><issn>0362-2436</issn><eissn>1528-1159</eissn><coden>SPINDD</coden><abstract>A prospective double-blind randomized trial in 28 patients.
To assess the clinical effect of percutaneous intradiscal radiofrequency thermocoagulation for reducing pain, functional disability, and physical impairment in patients with chronic discogenic low back pain.
Chronic discogenic low back pain is a challenging problem in western countries. A treatment option is radiofrequency heating of the affected disc. Its clinical efficacy has never been formally tested in a controlled trial.
Twenty-eight patients with a history of at least 1 year of chronic low back pain were selected on the basis of a diagnostic anesthetization of the lower intervertebral discs. Only patients with one putative painful level were selected and randomly assigned to one of two treatment groups. Each patient in the radiofrequency treatment group (n = 13) received a 90-second 70 C lesion of the intervertebral disc. Patients in the control group (n = 15) underwent the same procedure, but without use of radiofrequency current. Both the treating physician and the patients were blinded to the group assignment. Before treatment, physical impairment, rating of pain, the degree of disability, and quality of life were assessed by a blinded investigator.
Eight weeks after treatment, there was one success in the radiofrequency group (n = 13) and two in the control group (n = 15). The adjusted and unadjusted odds ratio was 0.5 and 1.1, respectively (not significant). Also, visual analog scores for pain, global perceived effect, and the Oswestry disability scale showed no differences between the two groups.
Percutaneous intradiscal radiofrequency thermocoagulation (90 seconds, 70 C) is not effective in reducing chronic discogenic low back pain.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>11224865</pmid><doi>10.1097/00007632-200102010-00014</doi><tpages>6</tpages></addata></record> |
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| ispartof | Spine (Philadelphia, Pa. 1976), 2001-02, Vol.26 (3), p.287-292 |
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| language | eng |
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| subjects | Adult Biological and medical sciences Catheter Ablation - adverse effects Catheter Ablation - instrumentation Catheter Ablation - methods Denervation - instrumentation Denervation - methods Diseases of the osteoarticular system. Orthopedic treatment Diskectomy, Percutaneous - adverse effects Diskectomy, Percutaneous - instrumentation Diskectomy, Percutaneous - methods Female Humans Intervertebral Disc - innervation Intervertebral Disc - pathology Intervertebral Disc - surgery Intervertebral Disc Displacement - complications Intervertebral Disc Displacement - pathology Intervertebral Disc Displacement - surgery Low Back Pain - etiology Low Back Pain - pathology Low Back Pain - surgery Male Medical sciences Middle Aged Nociceptors - cytology Nociceptors - physiology Nociceptors - surgery Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Spinal Nerves - cytology Spinal Nerves - physiology Spinal Nerves - surgery Treatment Outcome |
| title | Randomized controlled trial of percutaneous intradiscal radiofrequency thermocoagulation for chronic discogenic back pain : Lack of effect from a 90-second 70 C lesion |
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