Novel derivatives of chitosan and their antifungal activities in vitro

Three kinds of Schiff bases of carboxymethyl chitosan (CMCTS) were prepared, and their antifungal activities were assessed according to Jasso de Rodríguez’s method. The results indicated that 2-(2-hydroxybenzylideneamino)-6-carboxymethylchitosan (HNCMCTS) and 2-(5-chloro-2-hydroxybenzylideneamino)-6...

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Veröffentlicht in:	Carbohydrate research 2006-02, Vol.341 (3), p.351-354
Hauptverfasser:	Guo, Zhanyong, Chen, Rong, Xing, Ronge, Liu, Song, Yu, Huahua, Wang, Pibo, Li, Cuiping, Li, Pengcheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternaria - drug effects Alternaria - growth & development Antifungal activity Antifungal Agents - chemical synthesis Antifungal Agents - pharmacology Carboxymethyl chitosan Chitosan - analogs & derivatives Chitosan - chemical synthesis Chitosan - pharmacology Fusarium - drug effects Fusarium - growth & development In Vitro Techniques Microbial Sensitivity Tests Schiff bases
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Beschreibung
Zusammenfassung:	Three kinds of Schiff bases of carboxymethyl chitosan (CMCTS) were prepared, and their antifungal activities were assessed according to Jasso de Rodríguez’s method. The results indicated that 2-(2-hydroxybenzylideneamino)-6-carboxymethylchitosan (HNCMCTS) and 2-(5-chloro-2-hydroxybenzylideneamino)-6-carboxymethylchitosan (HCCMCTS) had better inhibitory effects than those of chitosan or CMCTS against Fusarium oxysporium f. sp. vasinfectum, Alternaria solani, and Valsa mali.
ISSN:	0008-6215 1873-426X
DOI:	10.1016/j.carres.2005.11.002