Prophylactic Surgery to Reduce the Risk of Gynecologic Cancers in the Lynch Syndrome

Women with the Lynch syndrome (hereditary nonpolyposis colorectal cancer) are at high risk for endometrial cancer and at increased risk for ovarian cancer. In this retrospective cohort study, there were no cases of either cancer among women who underwent prophylactic hysterectomy with bilateral salp...

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Veröffentlicht in:	The New England journal of medicine 2006-01, Vol.354 (3), p.261-269
Hauptverfasser:	Schmeler, Kathleen M, Lynch, Henry T, Chen, Lee-may, Munsell, Mark F, Soliman, Pamela T, Clark, Mary Beth, Daniels, Molly S, White, Kristin G, Boyd-Rogers, Stephanie G, Conrad, Peggy G, Yang, Kathleen Y, Rubin, Mary M, Sun, Charlotte C, Slomovitz, Brian M, Gershenson, David M, Lu, Karen H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cohort Studies Colorectal cancer Colorectal Neoplasms - epidemiology Colorectal Neoplasms - etiology Colorectal Neoplasms, Hereditary Nonpolyposis - complications Colorectal Neoplasms, Hereditary Nonpolyposis - genetics Colorectal Neoplasms, Hereditary Nonpolyposis - surgery Endometrial Neoplasms - epidemiology Endometrial Neoplasms - etiology Endometrial Neoplasms - prevention & control Female General aspects Germ-Line Mutation Gynecology Heredity Humans Hysterectomy Incidence Medical sciences Middle Aged Neoplasm Staging Ovarian cancer Ovarian Neoplasms - epidemiology Ovarian Neoplasms - etiology Ovarian Neoplasms - prevention & control Ovariectomy Peritoneal Neoplasms - epidemiology Peritoneal Neoplasms - etiology Peritoneal Neoplasms - prevention & control Postoperative Complications Preventive medicine Retrospective Studies Risk Surgery
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