Fluorous Mixture Synthesis of (−)-Dictyostatin and Three Stereoisomers

A mixture of four stereoisomers whose configurations are encoded by fluorous silyl protecting groups has been prepared and converted over 22 steps to a mixture of protected dictyostatins. Demixing by fluorous HPLC followed by removal of the fluorous protecting groups (detagging) provides dictyostati...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Organic letters 2006-01, Vol.8 (2), p.301-304
Hauptverfasser:	Fukui, Yoshikazu, Brückner, Arndt M, Shin, Youseung, Balachandran, Raghavan, Day, Billy W, Curran, Dennis P
Format:	Artikel
Sprache:	eng
Schlagworte:	Fluorine - chemistry Macrolides - chemical synthesis Macrolides - chemistry Molecular Structure Stereoisomerism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!