Effects of cytochalasin D-eluting stents on intimal hyperplasia in a porcine coronary artery model

To investigate whether cytochalasin D-eluting stents (CDES) suppress intimal hyperplasia in porcine coronary arteries and to compare the efficacy of paclitaxel and cytochalasin D as inhibitors of vascular smooth muscle cell (SMC) proliferation and platelet aggregation in vitro. Rabbit platelet-rich...

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Veröffentlicht in:	Cardiovascular research 2006-02, Vol.69 (2), p.536-544
Hauptverfasser:	SALU, Koen J, BOSMANS, Johan M, YANMING HUANG, HENDRIKS, Marc, VERHOEVEN, Michel, LEVELS, Anita, COOPER, Susan, DE SCHEERDER, Ivan K, VRINTS, Chris J, BULT, Hidde
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cardiology. Vascular system Cell Movement - drug effects Cell Proliferation - drug effects Cells, Cultured Coronary Angiography Coronary Restenosis - metabolism Coronary Restenosis - prevention & control Cytochalasin D - pharmacology Cytochalasin D - therapeutic use Dose-Response Relationship, Drug Hyperplasia Macrophages - drug effects Medical sciences Microscopy, Electron Models, Animal Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - drug effects Nucleic Acid Synthesis Inhibitors - pharmacology Nucleic Acid Synthesis Inhibitors - therapeutic use Paclitaxel - pharmacology Platelet Aggregation - drug effects Rabbits Random Allocation Stents Swine Tunica Intima - drug effects Tunica Intima - pathology
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