Rab5-activating protein 6, a novel endosomal protein with a role in endocytosis

Rab GTPases are regulators of membrane trafficking that cycle between active (GTP-bound) and inactive (GDP-bound) states. In this study, we report the identification of a new human Rab5 guanine nucleotide exchange factor (GEF), which we have named RAP6 (Rab5-activating protein 6). RAP6 contains a Ra...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2006-02, Vol.340 (3), p.967-975
Hauptverfasser:	Hunker, C.M., Galvis, A., Kruk, I., Giambini, H., Veisaga, M.L., Barbieri, M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cell Line Cell Membrane - metabolism CHO Cells Cloning, Molecular Cricetinae Cytosol - metabolism DNA, Complementary - metabolism Endocytosis Endosomes - metabolism Glutathione Transferase - metabolism Green Fluorescent Proteins - metabolism GTP Phosphohydrolases - metabolism Guanine Nucleotide Exchange Factors - chemistry Guanine Nucleotide Exchange Factors - physiology HeLa Cells Horseradish Peroxidase - metabolism Humans Intracellular Signaling Peptides and Proteins - chemistry Intracellular Signaling Peptides and Proteins - physiology Membrane Proteins - chemistry Membrane Proteins - physiology Membrane trafficking Microscopy, Fluorescence Molecular Sequence Data Oligopeptides - chemistry Peptides - chemistry Protein Binding Protein Structure, Tertiary Rab5 Receptor-mediated endocytosis Small GTPases Time Factors Transferrin - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!