Tracheal cartilage regeneration by slow release of basic fibroblast growth factor from a gelatin sponge

Objective We investigated whether implantation of a gelatin sponge, releasing basic fibroblast growth factor slowly (b-FGF) into a tracheal cartilage defect, would induce regeneration of autologous tracheal cartilage. Methods We created a 1-cm defect in the midventral portion of each of 10 consecuti...

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Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2007-07, Vol.134 (1), p.170-175
Hauptverfasser:	Igai, Hitoshi, MD, Yamamoto, Yasumichi, MD, Chang, Sung Soo, MD, Yamamoto, Masaya, MD, Tabata, Yasuhiko, MD, Yokomise, Hiroyasu, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cardiothoracic Surgery Cartilage - injuries Cartilage - pathology Cartilage - physiopathology Delayed-Action Preparations Dogs Drug Implants Fibroblast Growth Factor 2 - administration & dosage Foreign-Body Reaction - physiopathology Gelatin Medical sciences Regeneration - physiology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Surgical Sponges Trachea - injuries Trachea - pathology Trachea - physiopathology
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