Cutting Edge: Identification of E-Cadherin as a Ligand for the Murine Killer Cell Lectin-Like Receptor G1

The killer cell lectin-like receptor G1 (KLRG1) is expressed by NK cells and by T cells. In both humans and mice, KLRG1 identifies Ag-experienced T cells that are impaired in their proliferative capacity but are capable of performing effector functions. In this study, we identified E-cadherin as a l...

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Veröffentlicht in:	The Journal of immunology (1950) 2006-02, Vol.176 (3), p.1311-1315
Hauptverfasser:	Grundemann, Carsten, Bauer, Monika, Schweier, Oliver, von Oppen, Nanette, Lassing, Ute, Saudan, Philippe, Becker, Karl-Friedrich, Karp, Klaus, Hanke, Thomas, Bachmann, Martin F, Pircher, Hanspeter
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens - immunology Cadherins - biosynthesis Cadherins - metabolism Cadherins - physiology CD8-Positive T-Lymphocytes - cytology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism Cell Division - immunology Cell Line Growth Inhibitors - biosynthesis Growth Inhibitors - metabolism Growth Inhibitors - physiology Killer Cells, Lymphokine-Activated - immunology Killer Cells, Lymphokine-Activated - metabolism Ligands Melanoma, Experimental Mice Mice, Inbred C57BL Mice, Transgenic Receptors, Immunologic - genetics Receptors, Immunologic - metabolism
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