Standardized remission criteria in schizophrenia
Objective: Recent work has focussed on schizophrenia as a ‘deficit’ state but little attention has been paid to defining illness plasticity in terms of symptomatic remission. Method: A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A...
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Veröffentlicht in: | Acta psychiatrica Scandinavica 2006-02, Vol.113 (2), p.91-95 |
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container_title | Acta psychiatrica Scandinavica |
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creator | van Os, J. Burns, T. Cavallaro, R. Leucht, S. Peuskens, J. Helldin, L. Bernardo, M. Arango, C. Fleischhacker, W. Lachaux, B. Kane, J. M. |
description | Objective: Recent work has focussed on schizophrenia as a ‘deficit’ state but little attention has been paid to defining illness plasticity in terms of symptomatic remission.
Method: A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A. Lasser, S.R. Marder, D.R. Weinberger (2005) Am J Psychiatry 162: 441] is presented.
Results: The proposed definition of remission is conceptually viable, and can be easily implemented in clinical trials and clinical practice. Its increasing acceptance may reset expectations of treatment to a higher level, improve documentation of clinical status and facilitate dialogue on treatment expectations. The availability of validated outcome measures based on remission will enhance the conduct and reporting of clinical investigations, and could facilitate the design and interpretation of new studies on cognition and functional outcomes. While useful as a concept, it is important to consider that remission is distinct from recovery.
Conclusion: The introduction of standardized remission criteria may offer significant opportunities for clinical practice, health services research and clinical trials. |
doi_str_mv | 10.1111/j.1600-0447.2005.00659.x |
format | Article |
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Method: A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A. Lasser, S.R. Marder, D.R. Weinberger (2005) Am J Psychiatry 162: 441] is presented.
Results: The proposed definition of remission is conceptually viable, and can be easily implemented in clinical trials and clinical practice. Its increasing acceptance may reset expectations of treatment to a higher level, improve documentation of clinical status and facilitate dialogue on treatment expectations. The availability of validated outcome measures based on remission will enhance the conduct and reporting of clinical investigations, and could facilitate the design and interpretation of new studies on cognition and functional outcomes. While useful as a concept, it is important to consider that remission is distinct from recovery.
Conclusion: The introduction of standardized remission criteria may offer significant opportunities for clinical practice, health services research and clinical trials.</description><identifier>ISSN: 0001-690X</identifier><identifier>EISSN: 1600-0447</identifier><identifier>DOI: 10.1111/j.1600-0447.2005.00659.x</identifier><identifier>PMID: 16423159</identifier><identifier>CODEN: APYSA9</identifier><language>eng</language><publisher>Oxford, UK: Munksgaard International Publishers</publisher><subject>Adult and adolescent clinical studies ; Biological and medical sciences ; Chronic Disease ; Clinical Trials as Topic - standards ; Follow-Up Studies ; Humans ; Medical sciences ; Outcome Assessment (Health Care) - standards ; prognosis ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychoses ; psychotic disorders ; Remission Induction - methods ; Schizophrenia ; Schizophrenia - diagnosis ; Schizophrenia - therapy ; Schizophrenic Psychology ; therapeutics ; treatment outcome</subject><ispartof>Acta psychiatrica Scandinavica, 2006-02, Vol.113 (2), p.91-95</ispartof><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4359-8d913afed06faed3826291817027166caa1e72e9000713a0c10aa6de028be66f3</citedby><cites>FETCH-LOGICAL-c4359-8d913afed06faed3826291817027166caa1e72e9000713a0c10aa6de028be66f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1600-0447.2005.00659.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1600-0447.2005.00659.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17567899$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16423159$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van Os, J.</creatorcontrib><creatorcontrib>Burns, T.</creatorcontrib><creatorcontrib>Cavallaro, R.</creatorcontrib><creatorcontrib>Leucht, S.</creatorcontrib><creatorcontrib>Peuskens, J.</creatorcontrib><creatorcontrib>Helldin, L.</creatorcontrib><creatorcontrib>Bernardo, M.</creatorcontrib><creatorcontrib>Arango, C.</creatorcontrib><creatorcontrib>Fleischhacker, W.</creatorcontrib><creatorcontrib>Lachaux, B.</creatorcontrib><creatorcontrib>Kane, J. M.</creatorcontrib><title>Standardized remission criteria in schizophrenia</title><title>Acta psychiatrica Scandinavica</title><addtitle>Acta Psychiatr Scand</addtitle><description>Objective: Recent work has focussed on schizophrenia as a ‘deficit’ state but little attention has been paid to defining illness plasticity in terms of symptomatic remission.
Method: A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A. Lasser, S.R. Marder, D.R. Weinberger (2005) Am J Psychiatry 162: 441] is presented.
Results: The proposed definition of remission is conceptually viable, and can be easily implemented in clinical trials and clinical practice. Its increasing acceptance may reset expectations of treatment to a higher level, improve documentation of clinical status and facilitate dialogue on treatment expectations. The availability of validated outcome measures based on remission will enhance the conduct and reporting of clinical investigations, and could facilitate the design and interpretation of new studies on cognition and functional outcomes. While useful as a concept, it is important to consider that remission is distinct from recovery.
Conclusion: The introduction of standardized remission criteria may offer significant opportunities for clinical practice, health services research and clinical trials.</description><subject>Adult and adolescent clinical studies</subject><subject>Biological and medical sciences</subject><subject>Chronic Disease</subject><subject>Clinical Trials as Topic - standards</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Outcome Assessment (Health Care) - standards</subject><subject>prognosis</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychoses</subject><subject>psychotic disorders</subject><subject>Remission Induction - methods</subject><subject>Schizophrenia</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenia - therapy</subject><subject>Schizophrenic Psychology</subject><subject>therapeutics</subject><subject>treatment outcome</subject><issn>0001-690X</issn><issn>1600-0447</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMFu1DAQhi0EokvhFVAucEsYx_E4PnCoVlAqqlK1VO3NmjoT1Us2Wexdse3TN-mu2iu-WNZ8v-fXJ0QmoZDj-bIoJALkUFWmKAF0AYDaFttXYvY8eC1mACBztHBzIN6ltBifWkL9VhxIrEoltZ0JuFxT31BswgM3WeRlSCkMfeZjWHMMlIU-S_4uPAyru8h9oPfiTUtd4g_7-1Bcff_2e_4jP_11fDI_Os19pbTN68ZKRS03gC1xo-oSSytraaA0EtETSTYl27GTGUHwEoiwYSjrW0Zs1aH4vPt3FYe_G05rN1bz3HXU87BJzgBipVGPYL0DfRxSity6VQxLivdOgptsuYWbpLhJiptsuSdbbjtGP-53bG6X3LwE93pG4NMeoOSpayP1PqQXzmg0tZ24rzvuX-j4_r8LuKP5-SU-7cl3-ZDWvH3OU_zj0Cij3fXZsVNn9ue1uqhdqR4BYqOTcw</recordid><startdate>200602</startdate><enddate>200602</enddate><creator>van Os, J.</creator><creator>Burns, T.</creator><creator>Cavallaro, R.</creator><creator>Leucht, S.</creator><creator>Peuskens, J.</creator><creator>Helldin, L.</creator><creator>Bernardo, M.</creator><creator>Arango, C.</creator><creator>Fleischhacker, W.</creator><creator>Lachaux, B.</creator><creator>Kane, J. 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Psychiatry</topic><topic>Psychoses</topic><topic>psychotic disorders</topic><topic>Remission Induction - methods</topic><topic>Schizophrenia</topic><topic>Schizophrenia - diagnosis</topic><topic>Schizophrenia - therapy</topic><topic>Schizophrenic Psychology</topic><topic>therapeutics</topic><topic>treatment outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van Os, J.</creatorcontrib><creatorcontrib>Burns, T.</creatorcontrib><creatorcontrib>Cavallaro, R.</creatorcontrib><creatorcontrib>Leucht, S.</creatorcontrib><creatorcontrib>Peuskens, J.</creatorcontrib><creatorcontrib>Helldin, L.</creatorcontrib><creatorcontrib>Bernardo, M.</creatorcontrib><creatorcontrib>Arango, C.</creatorcontrib><creatorcontrib>Fleischhacker, W.</creatorcontrib><creatorcontrib>Lachaux, B.</creatorcontrib><creatorcontrib>Kane, J. M.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta psychiatrica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van Os, J.</au><au>Burns, T.</au><au>Cavallaro, R.</au><au>Leucht, S.</au><au>Peuskens, J.</au><au>Helldin, L.</au><au>Bernardo, M.</au><au>Arango, C.</au><au>Fleischhacker, W.</au><au>Lachaux, B.</au><au>Kane, J. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Standardized remission criteria in schizophrenia</atitle><jtitle>Acta psychiatrica Scandinavica</jtitle><addtitle>Acta Psychiatr Scand</addtitle><date>2006-02</date><risdate>2006</risdate><volume>113</volume><issue>2</issue><spage>91</spage><epage>95</epage><pages>91-95</pages><issn>0001-690X</issn><eissn>1600-0447</eissn><coden>APYSA9</coden><abstract>Objective: Recent work has focussed on schizophrenia as a ‘deficit’ state but little attention has been paid to defining illness plasticity in terms of symptomatic remission.
Method: A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A. Lasser, S.R. Marder, D.R. Weinberger (2005) Am J Psychiatry 162: 441] is presented.
Results: The proposed definition of remission is conceptually viable, and can be easily implemented in clinical trials and clinical practice. Its increasing acceptance may reset expectations of treatment to a higher level, improve documentation of clinical status and facilitate dialogue on treatment expectations. The availability of validated outcome measures based on remission will enhance the conduct and reporting of clinical investigations, and could facilitate the design and interpretation of new studies on cognition and functional outcomes. While useful as a concept, it is important to consider that remission is distinct from recovery.
Conclusion: The introduction of standardized remission criteria may offer significant opportunities for clinical practice, health services research and clinical trials.</abstract><cop>Oxford, UK</cop><pub>Munksgaard International Publishers</pub><pmid>16423159</pmid><doi>10.1111/j.1600-0447.2005.00659.x</doi><tpages>5</tpages></addata></record> |
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subjects | Adult and adolescent clinical studies Biological and medical sciences Chronic Disease Clinical Trials as Topic - standards Follow-Up Studies Humans Medical sciences Outcome Assessment (Health Care) - standards prognosis Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses psychotic disorders Remission Induction - methods Schizophrenia Schizophrenia - diagnosis Schizophrenia - therapy Schizophrenic Psychology therapeutics treatment outcome |
title | Standardized remission criteria in schizophrenia |
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