Standardized remission criteria in schizophrenia

Objective:  Recent work has focussed on schizophrenia as a ‘deficit’ state but little attention has been paid to defining illness plasticity in terms of symptomatic remission. Method:  A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A...

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Veröffentlicht in:Acta psychiatrica Scandinavica 2006-02, Vol.113 (2), p.91-95
Hauptverfasser: van Os, J., Burns, T., Cavallaro, R., Leucht, S., Peuskens, J., Helldin, L., Bernardo, M., Arango, C., Fleischhacker, W., Lachaux, B., Kane, J. M.
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container_end_page 95
container_issue 2
container_start_page 91
container_title Acta psychiatrica Scandinavica
container_volume 113
creator van Os, J.
Burns, T.
Cavallaro, R.
Leucht, S.
Peuskens, J.
Helldin, L.
Bernardo, M.
Arango, C.
Fleischhacker, W.
Lachaux, B.
Kane, J. M.
description Objective:  Recent work has focussed on schizophrenia as a ‘deficit’ state but little attention has been paid to defining illness plasticity in terms of symptomatic remission. Method:  A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A. Lasser, S.R. Marder, D.R. Weinberger (2005) Am J Psychiatry 162: 441] is presented. Results:  The proposed definition of remission is conceptually viable, and can be easily implemented in clinical trials and clinical practice. Its increasing acceptance may reset expectations of treatment to a higher level, improve documentation of clinical status and facilitate dialogue on treatment expectations. The availability of validated outcome measures based on remission will enhance the conduct and reporting of clinical investigations, and could facilitate the design and interpretation of new studies on cognition and functional outcomes. While useful as a concept, it is important to consider that remission is distinct from recovery. Conclusion:  The introduction of standardized remission criteria may offer significant opportunities for clinical practice, health services research and clinical trials.
doi_str_mv 10.1111/j.1600-0447.2005.00659.x
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The availability of validated outcome measures based on remission will enhance the conduct and reporting of clinical investigations, and could facilitate the design and interpretation of new studies on cognition and functional outcomes. While useful as a concept, it is important to consider that remission is distinct from recovery. 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M.</creatorcontrib><title>Standardized remission criteria in schizophrenia</title><title>Acta psychiatrica Scandinavica</title><addtitle>Acta Psychiatr Scand</addtitle><description>Objective:  Recent work has focussed on schizophrenia as a ‘deficit’ state but little attention has been paid to defining illness plasticity in terms of symptomatic remission. Method:  A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A. Lasser, S.R. Marder, D.R. Weinberger (2005) Am J Psychiatry 162: 441] is presented. Results:  The proposed definition of remission is conceptually viable, and can be easily implemented in clinical trials and clinical practice. Its increasing acceptance may reset expectations of treatment to a higher level, improve documentation of clinical status and facilitate dialogue on treatment expectations. The availability of validated outcome measures based on remission will enhance the conduct and reporting of clinical investigations, and could facilitate the design and interpretation of new studies on cognition and functional outcomes. While useful as a concept, it is important to consider that remission is distinct from recovery. Conclusion:  The introduction of standardized remission criteria may offer significant opportunities for clinical practice, health services research and clinical trials.</description><subject>Adult and adolescent clinical studies</subject><subject>Biological and medical sciences</subject><subject>Chronic Disease</subject><subject>Clinical Trials as Topic - standards</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Outcome Assessment (Health Care) - standards</subject><subject>prognosis</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychoses</subject><subject>psychotic disorders</subject><subject>Remission Induction - methods</subject><subject>Schizophrenia</subject><subject>Schizophrenia - diagnosis</subject><subject>Schizophrenia - therapy</subject><subject>Schizophrenic Psychology</subject><subject>therapeutics</subject><subject>treatment outcome</subject><issn>0001-690X</issn><issn>1600-0447</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMFu1DAQhi0EokvhFVAucEsYx_E4PnCoVlAqqlK1VO3NmjoT1Us2Wexdse3TN-mu2iu-WNZ8v-fXJ0QmoZDj-bIoJALkUFWmKAF0AYDaFttXYvY8eC1mACBztHBzIN6ltBifWkL9VhxIrEoltZ0JuFxT31BswgM3WeRlSCkMfeZjWHMMlIU-S_4uPAyru8h9oPfiTUtd4g_7-1Bcff_2e_4jP_11fDI_Os19pbTN68ZKRS03gC1xo-oSSytraaA0EtETSTYl27GTGUHwEoiwYSjrW0Zs1aH4vPt3FYe_G05rN1bz3HXU87BJzgBipVGPYL0DfRxSity6VQxLivdOgptsuYWbpLhJiptsuSdbbjtGP-53bG6X3LwE93pG4NMeoOSpayP1PqQXzmg0tZ24rzvuX-j4_r8LuKP5-SU-7cl3-ZDWvH3OU_zj0Cij3fXZsVNn9ue1uqhdqR4BYqOTcw</recordid><startdate>200602</startdate><enddate>200602</enddate><creator>van Os, J.</creator><creator>Burns, T.</creator><creator>Cavallaro, R.</creator><creator>Leucht, S.</creator><creator>Peuskens, J.</creator><creator>Helldin, L.</creator><creator>Bernardo, M.</creator><creator>Arango, C.</creator><creator>Fleischhacker, W.</creator><creator>Lachaux, B.</creator><creator>Kane, J. 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subjects Adult and adolescent clinical studies
Biological and medical sciences
Chronic Disease
Clinical Trials as Topic - standards
Follow-Up Studies
Humans
Medical sciences
Outcome Assessment (Health Care) - standards
prognosis
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
psychotic disorders
Remission Induction - methods
Schizophrenia
Schizophrenia - diagnosis
Schizophrenia - therapy
Schizophrenic Psychology
therapeutics
treatment outcome
title Standardized remission criteria in schizophrenia
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