Single turnover chemistry and regulation of O2 activation by the oxygenase component of naphthalene 1,2-dioxygenase

Naphthalene 1,2-dioxygenase (NDOS) is a three-component enzyme that catalyzes cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene formation from naphthalene, O2, and NADH. We have determined the conditions for a single turnover of NDOS for the first time and studied the regulation of catalysis. As isolated...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 2001-01, Vol.276 (3), p.1945-1953
Hauptverfasser:	Wolfe, M D, Parales, J V, Gibson, D T, Lipscomb, J D
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalysis Dioxygenases Electron Spin Resonance Spectroscopy Multienzyme Complexes - metabolism Oxidation-Reduction Oxygen - metabolism Oxygenases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!