Identification and Clinical Significance of Mobilized Endothelial Progenitor Cells in Tumor Vasculogenesis of Hepatocellular Carcinoma

Purpose: To investigate the distribution, frequency, and clinical significance of mobilized endothelial progenitor cells (EPC) in hepatocellular carcinoma (HCC). Experimental Design: In healthy controls and patients with HCC, the frequency of circulating EPCs was determined by colony-forming assays,...

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Veröffentlicht in:	Clinical cancer research 2007-07, Vol.13 (13), p.3814-3824
Hauptverfasser:	Yu, Decai, Sun, Xitai, Qiu, Yudong, Zhou, Jianxing, Wu, Yafu, Zhuang, Lingyuan, Chen, Jun, Ding, Yitao
Format:	Artikel
Sprache:	eng
Schlagworte:	AC133 AC133 Antigen Adult Antigens, CD - biosynthesis Antigens, CD34 - biosynthesis Antineoplastic agents Biological and medical sciences Biomarkers, Tumor - metabolism Carcinoma, Hepatocellular - diagnosis Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Endothelial Cells - cytology Endothelial progenitor cells Female Gastroenterology. Liver. Pancreas. Abdomen Glycoproteins - biosynthesis Hepatocellular carcinoma Humans Liver Neoplasms - diagnosis Liver Neoplasms - metabolism Liver Neoplasms - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Neovascularization Neovascularization, Pathologic Peptides Pharmacology. Drug treatments Platelet-Derived Growth Factor - biosynthesis Postal vasculogenesis Proto-Oncogene Proteins c-sis Stem Cells - cytology Tumors Vascular Endothelial Growth Factor A - blood
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