Development of cortical GABAergic circuits and its implications for neurodevelopmental disorders

GABAergic interneurons powerfully control the function of cortical networks. In addition, they strongly regulate cortical development by modulating several cellular processes such as neuronal proliferation, migration, differentiation and connectivity. Not surprisingly, aberrant development of GABAer...

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Veröffentlicht in:	Clinical genetics 2007-07, Vol.72 (1), p.1-8
1. Verfasser:	Di Cristo, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Autistic Disorder - etiology Biological and medical sciences Brain Brain Diseases - etiology Brain Diseases - metabolism Cerebral Cortex - growth & development Cerebral Cortex - metabolism cortex development-GABA Developmental disabilities Fundamental and applied biological sciences. Psychology gamma-Aminobutyric Acid - metabolism General aspects. Genetic counseling Genetics of eukaryotes. Biological and molecular evolution Humans inhibition interneurons Interneurons - metabolism Medical genetics Medical sciences Molecular and cellular biology Nerve Net - growth & development Nerve Net - metabolism Neurons Neurotransmitters Schizophrenia - etiology Tourette Syndrome - etiology
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