Congenital factor XIII deficiency in Switzerland: from the worldwide first case in 1960 to its molecular characterisation in 2005

Coagulation factor XIII (FXIII) has a major role in the final stage of blood coagulation, is important for wound healing and maintaining pregnancy. Severe congenital FXIII deficiency is a rare disorder with 1 patient in 1-3 million. Untreated, it causes bleeding events, with intracranial haemorrhage...

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Veröffentlicht in:	Swiss medical weekly 2007-05, Vol.137 (19-20), p.272-278
Hauptverfasser:	Schroeder, V, Durrer, D, Meili, E, Schubiger, G, Kohler, H P
Format:	Artikel
Sprache:	eng
Schlagworte:	Child Factor XIII - therapeutic use Factor XIII Deficiency - congenital Factor XIII Deficiency - diagnosis Factor XIII Deficiency - epidemiology Factor XIII Deficiency - genetics Factor XIII Deficiency - therapy Hemorrhage - congenital Humans Incidence Male Switzerland - epidemiology
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