Calculation of mitral regurgitant orifice area with use of a simplified proximal convergence method: Initial clinical application
To validate a previously proposed simplified proximal flow convergence method for calculating mitral regurgitant orifice area (ROA), a prospective study was conducted in ambulatory patients and in patients undergoing open heart surgery. Assuming a pressure difference between the left ventricle and l...
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| Veröffentlicht in: | Journal of the American Society of Echocardiography 2001-03, Vol.14 (3), p.180-185 |
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| creator | Pu, Min Prior, David L. Fan, Xiaoxue Asher, Craig R. Vasquez, Connie Griffin, Brian P. Thomas, James D. |
| description | To validate a previously proposed simplified proximal flow convergence method for calculating mitral regurgitant orifice area (ROA), a prospective study was conducted in ambulatory patients and in patients undergoing open heart surgery. Assuming a pressure difference between the left ventricle and left atrium of approximately 100 mm Hg (jet velocity [vp] 500 cm/s) and setting the color aliasing velocity (va) to 40 cm/s, we simplified the conventional proximal convergence method formula (ROA = 2πr2va/vp) to r2/2, where r is the radius of the proximal convergence isovelocity hemisphere. For 57 ambulatory patients with a wide range of mitral regurgitant severity (1 to 4+), ROA was calculated by the conventional (x) and simplified (y) methods, demonstrating excellent accuracy (r = 0.92; P |
| doi_str_mv | 10.1067/mje.2001.110139 |
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Assuming a pressure difference between the left ventricle and left atrium of approximately 100 mm Hg (jet velocity [vp] 500 cm/s) and setting the color aliasing velocity (va) to 40 cm/s, we simplified the conventional proximal convergence method formula (ROA = 2πr2va/vp) to r2/2, where r is the radius of the proximal convergence isovelocity hemisphere. For 57 ambulatory patients with a wide range of mitral regurgitant severity (1 to 4+), ROA was calculated by the conventional (x) and simplified (y) methods, demonstrating excellent accuracy (r = 0.92; P <.001; ΔROA [y − x] = 0.004 ± 0.08 cm2). For 24 intraoperative patients, ROA calculated by the simplified formula (y) correlated well with the pulsed Doppler-thermodilution method (x) (r = 0.84; P <.01; ΔROA [y − x] = −0.002 ± 0.08cm2). This simplified proximal convergence formula yields an accurate assessment of ROA for a wide range of regurgitant severity, while the time required for this measurement is shortened by half (1.5 ± 0.5 minutes versus 3.2 ± 0.7 minutes). This may increase the frequency of calculating ROA in the clinical laboratory. (J Am Soc Echocardiogr 2001;14:180-5.)</description><identifier>ISSN: 0894-7317</identifier><identifier>EISSN: 1097-6795</identifier><identifier>DOI: 10.1067/mje.2001.110139</identifier><identifier>PMID: 11241013</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Aged ; Echocardiography, Doppler - methods ; Female ; Humans ; Image Processing, Computer-Assisted ; Male ; Middle Aged ; Mitral Valve Insufficiency - diagnostic imaging ; Mitral Valve Insufficiency - physiopathology ; Mitral Valve Insufficiency - surgery ; Models, Cardiovascular ; Models, Structural ; Prospective Studies ; Space life sciences ; Thermodilution</subject><ispartof>Journal of the American Society of Echocardiography, 2001-03, Vol.14 (3), p.180-185</ispartof><rights>2001 American Society of Echocardiography</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c343t-453e24a2f56b42a109895fbf907064ad969be5127d1941d14a6d78467965c8ea3</citedby><cites>FETCH-LOGICAL-c343t-453e24a2f56b42a109895fbf907064ad969be5127d1941d14a6d78467965c8ea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0894731701272411$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11241013$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pu, Min</creatorcontrib><creatorcontrib>Prior, David L.</creatorcontrib><creatorcontrib>Fan, Xiaoxue</creatorcontrib><creatorcontrib>Asher, Craig R.</creatorcontrib><creatorcontrib>Vasquez, Connie</creatorcontrib><creatorcontrib>Griffin, Brian P.</creatorcontrib><creatorcontrib>Thomas, James D.</creatorcontrib><title>Calculation of mitral regurgitant orifice area with use of a simplified proximal convergence method: Initial clinical application</title><title>Journal of the American Society of Echocardiography</title><addtitle>J Am Soc Echocardiogr</addtitle><description>To validate a previously proposed simplified proximal flow convergence method for calculating mitral regurgitant orifice area (ROA), a prospective study was conducted in ambulatory patients and in patients undergoing open heart surgery. Assuming a pressure difference between the left ventricle and left atrium of approximately 100 mm Hg (jet velocity [vp] 500 cm/s) and setting the color aliasing velocity (va) to 40 cm/s, we simplified the conventional proximal convergence method formula (ROA = 2πr2va/vp) to r2/2, where r is the radius of the proximal convergence isovelocity hemisphere. For 57 ambulatory patients with a wide range of mitral regurgitant severity (1 to 4+), ROA was calculated by the conventional (x) and simplified (y) methods, demonstrating excellent accuracy (r = 0.92; P <.001; ΔROA [y − x] = 0.004 ± 0.08 cm2). For 24 intraoperative patients, ROA calculated by the simplified formula (y) correlated well with the pulsed Doppler-thermodilution method (x) (r = 0.84; P <.01; ΔROA [y − x] = −0.002 ± 0.08cm2). This simplified proximal convergence formula yields an accurate assessment of ROA for a wide range of regurgitant severity, while the time required for this measurement is shortened by half (1.5 ± 0.5 minutes versus 3.2 ± 0.7 minutes). This may increase the frequency of calculating ROA in the clinical laboratory. 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Assuming a pressure difference between the left ventricle and left atrium of approximately 100 mm Hg (jet velocity [vp] 500 cm/s) and setting the color aliasing velocity (va) to 40 cm/s, we simplified the conventional proximal convergence method formula (ROA = 2πr2va/vp) to r2/2, where r is the radius of the proximal convergence isovelocity hemisphere. For 57 ambulatory patients with a wide range of mitral regurgitant severity (1 to 4+), ROA was calculated by the conventional (x) and simplified (y) methods, demonstrating excellent accuracy (r = 0.92; P <.001; ΔROA [y − x] = 0.004 ± 0.08 cm2). For 24 intraoperative patients, ROA calculated by the simplified formula (y) correlated well with the pulsed Doppler-thermodilution method (x) (r = 0.84; P <.01; ΔROA [y − x] = −0.002 ± 0.08cm2). This simplified proximal convergence formula yields an accurate assessment of ROA for a wide range of regurgitant severity, while the time required for this measurement is shortened by half (1.5 ± 0.5 minutes versus 3.2 ± 0.7 minutes). This may increase the frequency of calculating ROA in the clinical laboratory. (J Am Soc Echocardiogr 2001;14:180-5.)</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>11241013</pmid><doi>10.1067/mje.2001.110139</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged Echocardiography, Doppler - methods Female Humans Image Processing, Computer-Assisted Male Middle Aged Mitral Valve Insufficiency - diagnostic imaging Mitral Valve Insufficiency - physiopathology Mitral Valve Insufficiency - surgery Models, Cardiovascular Models, Structural Prospective Studies Space life sciences Thermodilution |
| title | Calculation of mitral regurgitant orifice area with use of a simplified proximal convergence method: Initial clinical application |
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