Nucleosomes Positioned by ORC Facilitate the Initiation of DNA Replication

The packaging of eukaryotic DNA into nucleosomes is a critical regulator of nuclear events. To address the interplay between chromatin and replication initiation, we have assessed the determinants and function of the nucleosomal configuration of S. cerevisiae replication origins. Using in vitro and...

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Veröffentlicht in:	Molecular cell 2001, Vol.7 (1), p.21-30
Hauptverfasser:	Lipford, J.Russell, Bell, Stephen P
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatin - genetics DNA Replication - physiology DNA, Fungal - physiology DNA-Binding Proteins - physiology Fungal Proteins - physiology In Vitro Techniques Nucleosomes - genetics origin recognition complex Plasmids - genetics Replication Origin - genetics Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Transcription Factors - physiology Transcription, Genetic - physiology
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