Molecular genetic analysis of two human sperm fibrous sheath proteins, AKAP4 and AKAP3, in men with dysplasia of the fibrous sheath

Dysplasia of the fibrous sheath (DFS) is characterized by male infertility, asthenozoospermia, and morphologically abnormal flagella that possess a severely malformed fibrous sheath. In many cases, DFS is familial, suggesting a genetic component. Human AKAP4 and AKAP3 are structural proteins of the...

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Veröffentlicht in:	Journal of andrology 2001-03, Vol.22 (2), p.302-315
Hauptverfasser:	Turner, R. M, Musse, M. P, Mandal, A, Klotz, K, Jayes, F. C, Herr, J. C, Gerton, G. L, Moss, S. B, Chemes, H. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AKAP Base Sequence Biological and medical sciences Carrier Proteins - genetics DNA Primers Electrophoresis, Polyacrylamide Gel genetic infertility Genital Diseases, Male - genetics Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Isoelectric Focusing Male Male genital diseases male infertility Medical sciences Microscopy, Immunoelectron Non tumoral diseases Polymerase Chain Reaction Spermatozoa - metabolism
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