Searching for the physiological function of 17beta-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus: studies of substrate specificity and expression analysis

17beta-hydroxysteroid dehydrogenase from the filamentous fungus Cochliobolus lunatus (17beta-HSDcl) has recently been characterized. Since its function is still unclear, we performed substrate specificity studies to obtain some indications about its physiological function. Different steroids were st...

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Veröffentlicht in:	Molecular and cellular endocrinology 2001-01, Vol.171 (1-2), p.193-198
Hauptverfasser:	Lanisnik Rizner, T, Stojan, J, Adamski, J
Format:	Artikel
Sprache:	eng
Schlagworte:	17-Hydroxysteroid Dehydrogenases - analysis 17-Hydroxysteroid Dehydrogenases - genetics 17-Hydroxysteroid Dehydrogenases - metabolism Androgens - metabolism Androstenedione - metabolism Ascomycota - enzymology Carbenoxolone - pharmacology Enzyme Inhibitors - pharmacology Estrogens - metabolism Estrone - metabolism Etiocholanolone - analogs & derivatives Etiocholanolone - metabolism Fungal Proteins - metabolism Gene Expression Quercetin - pharmacology Recombinant Proteins - metabolism Substrate Specificity
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