Effect of the molecular weight of poly(ε-caprolactone-co- dl-lactide) on toremifene citrate release from copolymer/silica xerogel composites

The purpose of this study was to develop a biodegradable polymeric carrier system for toremifene citrate based on ε-caprolactone/ dl-lactide copolymers and silica xerogel. The effect of the molecular weight of poly(ε-caprolactone-co- dl-lactide) affecting the release rate of toremifene citrate from...

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Veröffentlicht in:	International journal of pharmaceutics 2001-01, Vol.212 (1), p.121-130
Hauptverfasser:	Rich, J, Kortesuo, P, Ahola, M, Yli-Urpo, A, Kiesvaara, J, Seppälä, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antineoplastic Agents, Hormonal - administration & dosage Biodegradable polymers Biological and medical sciences Drug release General aspects General pharmacology Hydrolysis Medical sciences Molecular Weight Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Poly(?-caprolactone-co- dl lactide) Polyesters - administration & dosage Polyesters - chemistry Silica Gel Silica xerogel Silicon Dioxide - administration & dosage Solubility Temperature Time Factors Toremifene - administration & dosage Toremifene - chemistry Toremifene citrate
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