Serial Analysis of Gene Expression in Differentiated Cultures of Human Epidermal Keratinocytes

Keratinocyte gene expression was surveyed more comprehensively than before, by means of serial analysis of gene expression. A total of 25,694 tags derived from expressed mRNA, were analyzed in a model for normal differentiation and in a model where cultured keratinocytes were stimulated for a prolon...

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Veröffentlicht in:	Journal of investigative dermatology 2001-01, Vol.116 (1), p.12-22
Hauptverfasser:	Jansen, Bastiaan J.H., van Ruissen, Fred, de Jongh, Gys, Zeeuwen, Patrick L.J.M., Schalkwijk, Joost
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - genetics Biological and medical sciences Blotting, Northern cell culture Cell Differentiation - genetics Cell Survival - genetics Cells, Cultured - drug effects Cells, Cultured - physiology cytokines Cytoskeletal Proteins - genetics Dermatology differentiation epidermis Epidermis - cytology Gene Expression - drug effects genetics Humans Investigative techniques, diagnostic techniques (general aspects) Keratinocytes - cytology Keratinocytes - drug effects Keratinocytes - metabolism Medical sciences Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques RNA, Messenger - genetics Tumor Necrosis Factor-alpha - pharmacology
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