Genetic Information, Genomic Technologies, and the Future of Drug Discovery
The completion of the first draft of the human genome has provided an unprecedented opportunity to understand the genetic and molecular basis of disease. Parallel developments of new biological technologies, such as transcript profiling, allow scientists to examine almost any biological system in hi...
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| Veröffentlicht in: | JAMA : the journal of the American Medical Association 2001-02, Vol.285 (5), p.551-555 |
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| container_issue | 5 |
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| container_title | JAMA : the journal of the American Medical Association |
| container_volume | 285 |
| creator | Bumol, Thomas F Watanabe, August M |
| description | The completion of the first draft of the human genome has provided an
unprecedented opportunity to understand the genetic and molecular basis of
disease. Parallel developments of new biological technologies, such as transcript
profiling, allow scientists to examine almost any biological system in high
molecular resolution. Contemporary drug discovery research is now focusing
on the identification and validation of pharmaceutical targets in the molecular
pathways/systems embedded in this information. Novel therapeutic interventions
are being developed and evaluated as a result of this research which will
be the basis of innovative pharmaceuticals of the future. |
| doi_str_mv | 10.1001/jama.285.5.551 |
| format | Article |
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profiling, allow scientists to examine almost any biological system in high
molecular resolution. Contemporary drug discovery research is now focusing
on the identification and validation of pharmaceutical targets in the molecular
pathways/systems embedded in this information. Novel therapeutic interventions
are being developed and evaluated as a result of this research which will
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unprecedented opportunity to understand the genetic and molecular basis of
disease. Parallel developments of new biological technologies, such as transcript
profiling, allow scientists to examine almost any biological system in high
molecular resolution. Contemporary drug discovery research is now focusing
on the identification and validation of pharmaceutical targets in the molecular
pathways/systems embedded in this information. Novel therapeutic interventions
are being developed and evaluated as a result of this research which will
be the basis of innovative pharmaceuticals of the future.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Biotechnology</subject><subject>Disease</subject><subject>Drug Design</subject><subject>Drug Industry - trends</subject><subject>Evaluation Studies as Topic</subject><subject>General aspects. 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Genetic counseling</topic><topic>Genetics</topic><topic>Genome, Human</topic><topic>Genomics</topic><topic>Human Genome Project</topic><topic>Humans</topic><topic>Medical genetics</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Medical technology</topic><topic>Molecular biology</topic><topic>Research - trends</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bumol, Thomas F</creatorcontrib><creatorcontrib>Watanabe, August M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>JAMA : the journal of the American Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bumol, Thomas F</au><au>Watanabe, August M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genetic Information, Genomic Technologies, and the Future of Drug Discovery</atitle><jtitle>JAMA : the journal of the American Medical Association</jtitle><addtitle>JAMA</addtitle><date>2001-02-07</date><risdate>2001</risdate><volume>285</volume><issue>5</issue><spage>551</spage><epage>555</epage><pages>551-555</pages><issn>0098-7484</issn><eissn>1538-3598</eissn><coden>JAMAAP</coden><abstract>The completion of the first draft of the human genome has provided an
unprecedented opportunity to understand the genetic and molecular basis of
disease. Parallel developments of new biological technologies, such as transcript
profiling, allow scientists to examine almost any biological system in high
molecular resolution. Contemporary drug discovery research is now focusing
on the identification and validation of pharmaceutical targets in the molecular
pathways/systems embedded in this information. Novel therapeutic interventions
are being developed and evaluated as a result of this research which will
be the basis of innovative pharmaceuticals of the future.</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>11176857</pmid><doi>10.1001/jama.285.5.551</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0098-7484 |
| ispartof | JAMA : the journal of the American Medical Association, 2001-02, Vol.285 (5), p.551-555 |
| issn | 0098-7484 1538-3598 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70646005 |
| source | MEDLINE; American Medical Association Journals |
| subjects | Animals Biological and medical sciences Biotechnology Disease Drug Design Drug Industry - trends Evaluation Studies as Topic General aspects. Genetic counseling Genetics Genome, Human Genomics Human Genome Project Humans Medical genetics Medical research Medical sciences Medical technology Molecular biology Research - trends |
| title | Genetic Information, Genomic Technologies, and the Future of Drug Discovery |
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