Prostate Cancer Progression and Survival in BRCA2 Mutation Carriers

Background Mutations in the BRCA2 gene are associated with an increased risk of prostate cancer, but it is not known whether they are associated with progression of the disease. We compared prostate cancer–specific survival, disease stage, and tumor grade between prostate cancer patients carrying th...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2007-06, Vol.99 (12), p.929-935
Hauptverfasser:	Tryggvadóttir, Laufey, Vidarsdóttir, Linda, Thorgeirsson, Tryggvi, Jonasson, Jon Gunnlaugur, Ólafsdóttir, Elinborg Jona, Ólafsdóttir, Gudridur Helga, Rafnar, Thorunn, Thorlacius, Steinunn, Jonsson, Eirikur, Eyfjord, Jorunn Erla, Tulinius, Hrafn
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Case-Control Studies Disease Progression Genes, BRCA2 Genetics Germ-Line Mutation Humans Iceland - epidemiology Male Medical prognosis Medical sciences Mutation Neoplasm Staging Nephrology. Urinary tract diseases Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - mortality Prostatic Neoplasms - pathology Risk factors Tumors Tumors of the urinary system Urinary tract. Prostate gland
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