Luteinizing hormone-dependent activity and luteinizing hormone-independent differentiation of rat fetal Leydig cells

Addition of 5×10 −2 U/ml recombinant luteinizing hormone (LH) to testes from fetuses at 16.5 day post conception (dpc) cultured for 5 days increased the number of Leydig cells by 34% and the acute LH-stimulated testosterone production by 600%. To determine whether these positive effects of LH in vit...

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Veröffentlicht in:	Molecular and cellular endocrinology 2001-02, Vol.172 (1), p.193-202
Hauptverfasser:	Migrenne, Stéphanie, Pairault, Catherine, Racine, Chrystèle, Livera, Gabriel, Géloso, Annette, Habert, René
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - drug effects Cell Division - drug effects Differentiation Female Fetus Fetus - cytology Gestational Age Leydig cell Leydig Cells - cytology Leydig Cells - drug effects Luteinizing Hormone - pharmacology Male Masculinization Rats Rats, Wistar Steroidogenesis Testis - drug effects Testis - embryology Testis - growth & development Testosterone - metabolism Wolffian Ducts - drug effects Wolffian Ducts - embryology Wolffian Ducts - growth & development
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