Efficacy of Recombinant Circumsporozoite Protein Vaccine Regimens against Experimental Plasmodium falciparum Malaria

After initial successful evaluation of the circumsporozoite-based vaccine RTS,S/SBAS2, developed by SmithKline Beecham Biologicals with the Walter Reed Army Institute of Research, protective efficacy of several regimens against Plasmodium falciparum challenge was determined. A controlled phase 1/2a...

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Veröffentlicht in:	The Journal of infectious diseases 2001-02, Vol.183 (4), p.640-647
Hauptverfasser:	Kester, Kent E., McKinney, Denise A., Tornieporth, Nadia, Ockenhouse, Christian F., Heppner, D. Gray, Hall, Ted, Krzych, Urszula, Delchambre, Martine, Voss, Gerald, Dowler, Megan G., Palensky, Jolie, Wittes, Janet, Cohen, Joe, Ballou, W. Ripley
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Antibodies Antibodies, Protozoan - blood Antigens Biological and medical sciences circumsporozoites Dosage Female Fundamental and applied biological sciences. Psychology Geometric mean Hepatitis antigens Hepatitis B vaccines Human protozoal diseases Humans Infectious diseases Lymphocyte Activation Major Articles Malaria Malaria vaccine Malaria Vaccines - administration & dosage Malaria Vaccines - adverse effects Malaria Vaccines - immunology Malaria, Falciparum - prevention & control Male Medical sciences Microbiology Middle Aged Parasitic diseases Plasmodium falciparum Plasmodium falciparum - immunology Protozoal diseases Protozoan Proteins - genetics Protozoan Proteins - immunology Recombinant Proteins - immunology Sporozoites Vaccination Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Vaccines, Synthetic - administration & dosage Vaccines, Synthetic - immunology Virology
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