UVB-induced apoptosis of human dendritic cells: contribution by caspase-dependent and caspase-independent pathways

Dendritic cells (DCs) play a central role in the initiation and regulation of the immune response. The modalities by which DCs are committed to undergo apoptosis are poorly defined. Here it is shown that, unlike death receptor ligands, UVB radiation triggers apoptosis of human DCs very efficiently....

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