Sharpin, a Novel Postsynaptic Density Protein That Directly Interacts with the Shank Family of Proteins

The Shank family of proteins (also termed CortBP, ProSAP, or Synamon) is highly enriched in the postsynaptic density (PSD) of excitatory synapses in brain. Shank contains multiple domains for protein–protein interactions, including ankyrin repeats, SH3 domain, PDZ domain, SAM domain, and an extensiv...

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Veröffentlicht in:	Molecular and cellular neuroscience 2001-02, Vol.17 (2), p.385-397
Hauptverfasser:	Lim, Sangmi, Sala, Carlo, Yoon, Jiyoung, Park, Soochul, Kuroda, Shun'ichi, Sheng, Morgan, Kim, Eunjoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Animals Ankyrins - metabolism Brain Chemistry - physiology Carrier Proteins - analysis Carrier Proteins - genetics Carrier Proteins - metabolism Cells, Cultured Gene Expression - physiology In Vitro Techniques Molecular Sequence Data Nerve Tissue Proteins - chemistry Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Neurons - chemistry Neurons - cytology Neurons - metabolism postsynaptic density protein Precipitin Tests Protein Binding - physiology Protein Structure, Tertiary Rats RNA, Messenger - analysis Sequence Homology, Amino Acid shank protein sharpin protein Synapses - chemistry Synapses - metabolism Two-Hybrid System Techniques
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