Constitutive expression of c-myb mRNA in the adult rat brain

In this study, we demonstrated the c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior collicu...

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Veröffentlicht in:Brain research 2001-02, Vol.892 (1), p.203-207
Hauptverfasser: Shin, Dong Hoon, Lee, Hye Won, Jeon, Gye Sun, Lee, Hwa Young, Lee, Kyung Hoon, Cho, Sa Sun
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container_start_page 203
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creator Shin, Dong Hoon
Lee, Hye Won
Jeon, Gye Sun
Lee, Hwa Young
Lee, Kyung Hoon
Cho, Sa Sun
description In this study, we demonstrated the c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior colliculi and central gray. In the cerebellum, a diffuse signal was found in the granular layer while some positive cells were detected in the molecular layer as well. In addition, a number of cells showed intense signals in many nuclei of the medulla oblongata. The constitutive expression of c-myb mRNA in the different kinds of neural cells suggests that this gene might be involved in the normal function of these neurons.
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subjects Animals
Biochemistry and metabolism
Biological and medical sciences
Brain
Brain - physiology
c-myb
c-Myb protein
Central nervous system
Fundamental and applied biological sciences. Psychology
Genes, myb
In situ hybridization
Neurons - physiology
Organ Specificity
Prosencephalon - physiology
Proto-Oncogene Proteins c-myb - genetics
Rat
Rats
Rats, Sprague-Dawley
RNA, Messenger - analysis
Superior Colliculi - physiology
Transcription factor
Transcription, Genetic
Vertebrates: nervous system and sense organs
title Constitutive expression of c-myb mRNA in the adult rat brain
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