Constitutive expression of c-myb mRNA in the adult rat brain
In this study, we demonstrated the c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior collicu...
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Veröffentlicht in: | Brain research 2001-02, Vol.892 (1), p.203-207 |
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creator | Shin, Dong Hoon Lee, Hye Won Jeon, Gye Sun Lee, Hwa Young Lee, Kyung Hoon Cho, Sa Sun |
description | In this study, we demonstrated the
c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found
c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior colliculi and central gray. In the cerebellum, a diffuse signal was found in the granular layer while some positive cells were detected in the molecular layer as well. In addition, a number of cells showed intense signals in many nuclei of the medulla oblongata. The constitutive expression of
c-myb mRNA in the different kinds of neural cells suggests that this gene might be involved in the normal function of these neurons. |
doi_str_mv | 10.1016/S0006-8993(00)03300-X |
format | Article |
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c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found
c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior colliculi and central gray. In the cerebellum, a diffuse signal was found in the granular layer while some positive cells were detected in the molecular layer as well. In addition, a number of cells showed intense signals in many nuclei of the medulla oblongata. The constitutive expression of
c-myb mRNA in the different kinds of neural cells suggests that this gene might be involved in the normal function of these neurons.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/S0006-8993(00)03300-X</identifier><identifier>PMID: 11172765</identifier><identifier>CODEN: BRREAP</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Animals ; Biochemistry and metabolism ; Biological and medical sciences ; Brain ; Brain - physiology ; c-myb ; c-Myb protein ; Central nervous system ; Fundamental and applied biological sciences. Psychology ; Genes, myb ; In situ hybridization ; Neurons - physiology ; Organ Specificity ; Prosencephalon - physiology ; Proto-Oncogene Proteins c-myb - genetics ; Rat ; Rats ; Rats, Sprague-Dawley ; RNA, Messenger - analysis ; Superior Colliculi - physiology ; Transcription factor ; Transcription, Genetic ; Vertebrates: nervous system and sense organs</subject><ispartof>Brain research, 2001-02, Vol.892 (1), p.203-207</ispartof><rights>2001 Elsevier Science B.V.</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-4e1dad61947f203321aacb35174a2845c6e53c0342183232d0cff33d3aca9b4f3</citedby><cites>FETCH-LOGICAL-c421t-4e1dad61947f203321aacb35174a2845c6e53c0342183232d0cff33d3aca9b4f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0006-8993(00)03300-X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1121279$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11172765$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shin, Dong Hoon</creatorcontrib><creatorcontrib>Lee, Hye Won</creatorcontrib><creatorcontrib>Jeon, Gye Sun</creatorcontrib><creatorcontrib>Lee, Hwa Young</creatorcontrib><creatorcontrib>Lee, Kyung Hoon</creatorcontrib><creatorcontrib>Cho, Sa Sun</creatorcontrib><title>Constitutive expression of c-myb mRNA in the adult rat brain</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>In this study, we demonstrated the
c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found
c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior colliculi and central gray. In the cerebellum, a diffuse signal was found in the granular layer while some positive cells were detected in the molecular layer as well. In addition, a number of cells showed intense signals in many nuclei of the medulla oblongata. The constitutive expression of
c-myb mRNA in the different kinds of neural cells suggests that this gene might be involved in the normal function of these neurons.</description><subject>Animals</subject><subject>Biochemistry and metabolism</subject><subject>Biological and medical sciences</subject><subject>Brain</subject><subject>Brain - physiology</subject><subject>c-myb</subject><subject>c-Myb protein</subject><subject>Central nervous system</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genes, myb</subject><subject>In situ hybridization</subject><subject>Neurons - physiology</subject><subject>Organ Specificity</subject><subject>Prosencephalon - physiology</subject><subject>Proto-Oncogene Proteins c-myb - genetics</subject><subject>Rat</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>RNA, Messenger - analysis</subject><subject>Superior Colliculi - physiology</subject><subject>Transcription factor</subject><subject>Transcription, Genetic</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1L5TAQhoMoenT9CS65ENm9qDvJtE0LgsjBXYWDwn6AdyFNp2ykH8cklfXf2_PB6p1Xw8Dzzrw8jJ0IOBcg8m-_ACBPirLELwBfAREgedhhM1EomeQyhV02-48csMMQHqcVsYR9diCEUFLl2YxdzIc-RBfH6J6J07-lpxDc0POh4TbpXire_by74q7n8S9xU49t5N5EXnnj-k9srzFtoOPtPGJ_vl__nt8ki_sft_OrRWJTKWKSkqhNnYsyVY2cKkhhjK0wEyo1skgzm1OGFnCCC5Qoa7BNg1ijsaas0gaP2Nnm7tIPTyOFqDsXLLWt6WkYg1aQYwFF-SEolFICMZvAbANaP4TgqdFL7zrjX7QAvfKr1371Sp4G0Gu_-mHKfd4-GKuO6rfUVugEnG4BE6xpG29668I7TgqpVkUvNxhN2p4deR2so95S7TzZqOvBfdDkFSLOlQY</recordid><startdate>20010216</startdate><enddate>20010216</enddate><creator>Shin, Dong Hoon</creator><creator>Lee, Hye Won</creator><creator>Jeon, Gye Sun</creator><creator>Lee, Hwa Young</creator><creator>Lee, Kyung Hoon</creator><creator>Cho, Sa Sun</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20010216</creationdate><title>Constitutive expression of c-myb mRNA in the adult rat brain</title><author>Shin, Dong Hoon ; Lee, Hye Won ; Jeon, Gye Sun ; Lee, Hwa Young ; Lee, Kyung Hoon ; Cho, Sa Sun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-4e1dad61947f203321aacb35174a2845c6e53c0342183232d0cff33d3aca9b4f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Animals</topic><topic>Biochemistry and metabolism</topic><topic>Biological and medical sciences</topic><topic>Brain</topic><topic>Brain - physiology</topic><topic>c-myb</topic><topic>c-Myb protein</topic><topic>Central nervous system</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Genes, myb</topic><topic>In situ hybridization</topic><topic>Neurons - physiology</topic><topic>Organ Specificity</topic><topic>Prosencephalon - physiology</topic><topic>Proto-Oncogene Proteins c-myb - genetics</topic><topic>Rat</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>RNA, Messenger - analysis</topic><topic>Superior Colliculi - physiology</topic><topic>Transcription factor</topic><topic>Transcription, Genetic</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shin, Dong Hoon</creatorcontrib><creatorcontrib>Lee, Hye Won</creatorcontrib><creatorcontrib>Jeon, Gye Sun</creatorcontrib><creatorcontrib>Lee, Hwa Young</creatorcontrib><creatorcontrib>Lee, Kyung Hoon</creatorcontrib><creatorcontrib>Cho, Sa Sun</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shin, Dong Hoon</au><au>Lee, Hye Won</au><au>Jeon, Gye Sun</au><au>Lee, Hwa Young</au><au>Lee, Kyung Hoon</au><au>Cho, Sa Sun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Constitutive expression of c-myb mRNA in the adult rat brain</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>2001-02-16</date><risdate>2001</risdate><volume>892</volume><issue>1</issue><spage>203</spage><epage>207</epage><pages>203-207</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><coden>BRREAP</coden><abstract>In this study, we demonstrated the
c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found
c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior colliculi and central gray. In the cerebellum, a diffuse signal was found in the granular layer while some positive cells were detected in the molecular layer as well. In addition, a number of cells showed intense signals in many nuclei of the medulla oblongata. The constitutive expression of
c-myb mRNA in the different kinds of neural cells suggests that this gene might be involved in the normal function of these neurons.</abstract><cop>London</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>11172765</pmid><doi>10.1016/S0006-8993(00)03300-X</doi><tpages>5</tpages></addata></record> |
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subjects | Animals Biochemistry and metabolism Biological and medical sciences Brain Brain - physiology c-myb c-Myb protein Central nervous system Fundamental and applied biological sciences. Psychology Genes, myb In situ hybridization Neurons - physiology Organ Specificity Prosencephalon - physiology Proto-Oncogene Proteins c-myb - genetics Rat Rats Rats, Sprague-Dawley RNA, Messenger - analysis Superior Colliculi - physiology Transcription factor Transcription, Genetic Vertebrates: nervous system and sense organs |
title | Constitutive expression of c-myb mRNA in the adult rat brain |
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