Antioxidant alpha-lipoic acid and protein turnover in insulin-resistant rat muscle

We have shown previously that the antioxidant alpha-lipoic acid (ALA) can stimulate glucose transport and can enhance the stimulation of this process by insulin in skeletal muscle from insulin-resistant obese Zucker rats. As insulin can also acutely activate general protein synthesis and inhibit net...

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Veröffentlicht in:	Free radical biology & medicine 2001-02, Vol.30 (4), p.383-388
Hauptverfasser:	Weinstein, Randi B, Tritschler, Hans J, Henriksen, Erik J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidant Biological Transport - drug effects Female Free Radicals Glucose - metabolism In Vitro Techniques Insulin - pharmacology Insulin resistance Insulin Resistance - physiology Muscle Proteins - metabolism Muscle, Skeletal - drug effects Muscle, Skeletal - metabolism Obesity - metabolism Oxidation-Reduction Protein degradation Protein synthesis Rats Rats, Wistar Rats, Zucker Species Specificity Thioctic Acid - pharmacology
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