Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice

Tissue-specific gene inactivation using the Cre-loxP system has become an important tool to unravel functions of genes when the conventional null mutation is lethal. We report here the generation of a transgenic mouse line expressing Cre recombinase in endothelial cells. In order to avoid the produc...

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