An apparently dominant bipolar affective disorder (BPAD) locus on chromosome 20p11.2-q11.2 in a large Turkish pedigree

Bipolar affective disorder (BPAD), also known as manic-depressive illness, is a common complex, polygenic disorder characterised by recurrent cyclic episodes of mania and depression. Family, twin, and adoption studies strongly suggest a genetic predisposition/susceptibility to BPAD, but no genes hav...

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Veröffentlicht in:	European journal of human genetics : EJHG 2001-01, Vol.9 (1), p.39-44
Hauptverfasser:	Radhakrishna, U, Senol, S, Herken, H, Gucuyener, K, Gehrig, C, Blouin, J L, Akarsu, N A, Antonarakis, S E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoption Adult Affective disorders Aged Alleles Bipolar disorder Bipolar Disorder - genetics Bipolar Disorder - pathology Chromosome 20 Chromosome Banding Chromosome Mapping Chromosomes Chromosomes, Human, Pair 20 - genetics Depression DNA - genetics Family Health Family medical history Female Gene mapping Genes Genes, Dominant Genetics Genomes Genotype Haplotypes Hereditary diseases Heredity Humans Illnesses Linkage analysis Lithium Lod Score Male Microsatellite Repeats Middle Aged Mutation Pedigree Penetrance Phenotype Phenotypes Polygenic inheritance Remission Susceptibility Turkey
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