Thyroid hormone deficiency alters extracellular matrix protein expression in rat brain

The effects of thyroid hormone (T 3) deficiency on extracellular matrix protein expression were analyzed in newborn rat brain. In hypothyroid animals, a marked increase in the expression of 62 kDa protein was observed in cerebral hemispheres and midbrain, while the 51.6 kDa protein was increased in...

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Veröffentlicht in:	Brain research. Developmental brain research 2001-01, Vol.126 (1), p.121-124
Hauptverfasser:	Calloni, Giordano W., Alvarez-Silva, Marcio, Vituri, Cidônia, Trentin, Andréa G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Brain Cerebral Cortex - growth & development Cerebral Cortex - metabolism Extracellular matrix Extracellular Matrix Proteins - metabolism Female Fibronectin Fibronectins - metabolism Hypothyroidism Hypothyroidism - metabolism Mesencephalon - growth & development Mesencephalon - metabolism Proteoglycan Proteoglycans - metabolism Rats Rats, Wistar Thyroid hormone Triiodothyronine - deficiency
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