Sperm maturation in the epididymis: a new look at an old problem
The osmotic challenges facing maturing spermatozoa and their responses to them are discussed in relation to the concept of sperm maturation, defined as the increased ability of more distally recovered epididymal spermatozoa to fertilize eggs when inseminated into the female tract. One explanation co...
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Veröffentlicht in: | Asian journal of andrology 2007-07, Vol.9 (4), p.533-539 |
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description | The osmotic challenges facing maturing spermatozoa and their responses to them are discussed in relation to the concept of sperm maturation, defined as the increased ability of more distally recovered epididymal spermatozoa to fertilize eggs when inseminated into the female tract. One explanation could be that the more distal cells are better able to regulate their volume, and reach the oviducts, as a consequence of uptake of epididymal osmolytes. Increased motility, zona binding and oolemma fusion capacities are also acquired within the epididymis and are necessary for those cells that finally arrive at the site of fertilization. |
doi_str_mv | 10.1111/j.1745-7262.2007.00285.x |
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source | MEDLINE; Wiley Journals; DOAJ Directory of Open Access Journals |
subjects | Animals epididymal function Epididymis - physiology Female fertilization Fertilization - physiology Humans in vivo Infertility, Male - physiopathology Male Mammals Mice osmotic challenge Ovum - physiology sperm maturation Sperm Maturation - physiology Spermatozoa - physiology |
title | Sperm maturation in the epididymis: a new look at an old problem |
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