Polymorphisms in the genes for mGluR types 7 and 8: association studies with schizophrenia

A dysfunctional glutamatergic system has been implicated in the pathophysiology of schizophrenia. The group III metabotropic glutamate receptor (mGluR) types 7 and 8 presynaptically inhibit glutamate release, thereby modulating glutamatergic transmission in the brain. We conducted association studie...

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Veröffentlicht in:	Schizophrenia research 2001-01, Vol.47 (1), p.99-103
Hauptverfasser:	Bolonna, A.A., Kerwin, R.W., Munro, J., Arranz, M.J., Makoff, A.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Alleles Biological and medical sciences Female Gene Frequency - genetics Genotype Humans Male Medical sciences Metabotropic glutamate receptor Middle Aged Polymerase Chain Reaction Polymorphism, Genetic - genetics Polymorphism, Restriction Fragment Length Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Receptors, Metabotropic Glutamate - genetics Schizophrenia Schizophrenia - diagnosis Schizophrenia - genetics
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