Helicobacter pylori-mediated transcriptional regulation of the human beta-defensin 2 gene requires NF-kappaB

Human beta-defensin 2 (hBD-2) is an antimicrobial peptide involved in host defence against bacterial infection in epithelial tissues. Its levels are dramatically increased after bacterial infection. The involvement of NF-kappaB in Helicobacter pylori-mediated induction of hBD-2 promoter activity was...

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Veröffentlicht in:	Cellular microbiology 2001-02, Vol.3 (2), p.115-123
Hauptverfasser:	Wada, A, Ogushi, K, Kimura, T, Hojo, H, Mori, N, Suzuki, S, Kumatori, A, Se, M, Nakahara, Y, Nakamura, M, Moss, J, Hirayama, T
Format:	Artikel
Sprache:	eng
Schlagworte:	beta-Defensins - genetics Cell Line Gastric Mucosa - microbiology Gene Expression Regulation Helicobacter pylori - pathogenicity Humans NF-kappa B - metabolism Promoter Regions, Genetic Transcription, Genetic
Online-Zugang:	Volltext
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