Regulation of Invasion of Epithelial Ovarian Cancer by Transforming Growth Factor-β

Objective. The metastatic process in epithelial ovarian cancer is thought to involve surface shedding and subsequent dissemination of ovarian cancer cells, facilitated by localized proteolysis at the interface between ovarian cancer cells and peritoneal surfaces. The factors regulating the metastati...

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Veröffentlicht in:	Gynecologic oncology 2001-02, Vol.80 (2), p.245-253
Hauptverfasser:	Rodriguez, Gustavo C., Haisley, Camille, Hurteau, Jean, Moser, Tammy L., Whitaker, Regina, Bast, Robert C., Stack, Mary Sharon
Format:	Artikel
Sprache:	eng
Schlagworte:	Basement Membrane - cytology Biological and medical sciences Cell Adhesion - drug effects Cell Adhesion - physiology Cell Movement - drug effects Cell Movement - physiology Epithelial Cells - pathology Female Female genital diseases Gynecology. Andrology. Obstetrics Humans invasion Matrix Metalloproteinases - biosynthesis Medical sciences metalloproteinase metastasis Neoplasm Invasiveness ovarian carcinoma Ovarian Neoplasms - enzymology Ovarian Neoplasms - pathology Ovary - cytology Ovary - drug effects Ovary - enzymology Recombinant Proteins - pharmacology TGF-β Transforming Growth Factor beta - pharmacology Transforming Growth Factor beta - physiology Tumor Cells, Cultured - drug effects Tumors
Online-Zugang:	Volltext
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