Pregnancy and murine thyroiditis: thyroglobulin immunization leads to fetal loss in specific allogeneic pregnancies

Thyroid autoantibodies are risk factors in human pregnancy. To investigate the influence of autoimmune thyroiditis on pregnancy, we have studied the impact of murine experimental autoimmune thyroiditis (EAT) on pregnancy outcome by using thyroglobulin (Tg) immunized CBA/J (H2(k)) female mice. When T...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2001-02, Vol.142 (2), p.823-829
Hauptverfasser:	Imaizumi, M, Pritsker, A, Kita, M, Ahmad, L, Unger, P, Davies, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Division Cytokines - metabolism Female Fetal Death - etiology Histocompatibility Antigens Class II - analysis Immunization - adverse effects Lymphocyte Culture Test, Mixed Mice Mice, Inbred Strains Placenta - immunology Pregnancy - immunology Pregnancy Complications - physiopathology Thyroglobulin - immunology Thyroid Gland - physiopathology Thyroiditis, Autoimmune - pathology Thyroiditis, Autoimmune - physiopathology
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