The Efficiency of Simian Foamy Virus Vector Type-1 (SFV-1) in Nondividing Cells and in Human PBLs

Current retroviral vectors based on murine leukemia virus (MuLV) are unable to efficiently transduce nondividing cells. Lentiviruses, such as the human immunodeficiency virus 1 (HIV-1) are efficient at transducing nondividing, growth-arrested, and post-mitotic cells, but due to complex safety consid...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2001-02, Vol.280 (2), p.243-252
Hauptverfasser:	Mergia, Ayalew, Chari, Soumya, Kolson, Dennis L., Goodenow, Maureen M., Ciccarone, Tina
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals aphidicolin Cell Division Cell Line Cell Line, Transformed Cercopithecus aethiops COS Cells Foamy virus Genes, Reporter Genetic Vectors - genetics HeLa Cells Humans K562 Cells Lac Operon Leukocytes, Mononuclear - cytology Mice phytohemagglutinins Simian foamy virus 1 Spumavirus - genetics Spumavirus - physiology Tumor Cells, Cultured
Online-Zugang:	Volltext
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