Effects of anti-protozoal drugs and histopathological studies on trypanosome species

Abstract The trypanosomostatic and trypanosomicidal effects of four anti-protozoal drugs, namely halofantrine hydrochloride, chloroquine phosphate, benzoylmetronidazole and pyrimethamine, on species of trypanosomes, viz. Trypanosoma brucei brucei (MBOS/NG/94/NITR) Bassa strain, T. congolense (MBOS/N...

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Veröffentlicht in:	FEMS immunology and medical microbiology 2001-02, Vol.30 (1), p.73-83
Hauptverfasser:	Ogunbanwo, Jamiu A, Agbonlahor, Dennis E, Adamu, A, Dalyop, P, Elesha, Stephen O, Fagbenro-Beyioku, A.F
Format:	Artikel
Sprache:	eng
Schlagworte:	African trypanosomiasis Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiparasitic agents benzoylmetronidazole Biological and medical sciences Chloroquine Chloroquine - pharmacology Chloroquine - therapeutic use chloroquine phosphate Drugs Edema Female halofantrine hydrochloride Histopathology Humans In vivo methods and tests Inflammation Male Medical sciences Metronidazole - analogs & derivatives Metronidazole - pharmacology Metronidazole - therapeutic use Necrosis Organs Parasites Parasitic Sensitivity Tests Pharmacology. Drug treatments Phenanthrenes - pharmacology Phenanthrenes - therapeutic use Protozoa Pyrimethamine Pyrimethamine - pharmacology Pyrimethamine - therapeutic use Rats Species Treatment Trypanosoma - classification Trypanosoma - drug effects Trypanosoma brucei brucei Trypanosoma congolense Trypanosome Trypanosomiasis Trypanosomiasis - drug therapy Trypanosomiasis - parasitology Trypanosomiasis - pathology Vector-borne diseases
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