Hypoadiponectinemia in type 2 diabetes mellitus in men is associated with sympathetic overactivity as evaluated by cardiac 123I-metaiodobenzylguanidine scintigraphy

Hypoadiponectinemia is associated with insulin resistance. However, there is very limited information about the relationship between plasma adiponectin and cardiac autonomic nervous function. We tested the hypothesis that hypoadiponectinemia is associated with cardiac sympathetic overactivity in pat...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 2007-07, Vol.56 (7), p.919-924
Hauptverfasser:	Takahashi, Naohiko, Anan, Futoshi, Nakagawa, Mikiko, Yufu, Kunio, Shinohara, Tetsuji, Tsubone, Tetsuo, Goto, Koro, Masaki, Takayuki, Katsuragi, Isao, Tanaka, Katsuhiro, Kakuma, Testsuya, Hara, Masahide, Saikawa, Tetsunori, Yoshimatsu, Hironobu
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Iodobenzylguanidine Adiponectin - blood Aged Baroreflex Biological and medical sciences Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - physiopathology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Heart - diagnostic imaging Heart - innervation Heart Rate Humans Insulin Resistance Male Medical sciences Metabolic diseases Middle Aged Radionuclide Imaging Radiopharmaceuticals Sympathetic Nervous System - physiopathology
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Zusammenfassung:	Hypoadiponectinemia is associated with insulin resistance. However, there is very limited information about the relationship between plasma adiponectin and cardiac autonomic nervous function. We tested the hypothesis that hypoadiponectinemia is associated with cardiac sympathetic overactivity in patients with type 2 diabetes mellitus. Thirty-three male type 2 diabetic patients not on insulin treatment were classified into a hypoadiponectinemia group (plasma adiponectin concentration,
ISSN:	0026-0495 1532-8600
DOI:	10.1016/j.metabol.2007.02.005