Selective Deficits in the Omega-3 Fatty Acid Docosahexaenoic Acid in the Postmortem Orbitofrontal Cortex of Patients with Major Depressive Disorder

Background Epidemiological surveys and peripheral tissue (red blood cells/plasma) fatty acid composition studies suggest that omega-3 fatty acid deficiency is associated with major depressive disorder (MDD) and suicide. It was hypothesized that patients with MDD would exhibit lower frontal cortical...

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Veröffentlicht in:	Biological psychiatry (1969) 2007-07, Vol.62 (1), p.17-24
Hauptverfasser:	McNamara, Robert K, Hahn, Chang-Gyu, Jandacek, Ronald, Rider, Therese, Tso, Patrick, Stanford, Kevin E, Richtand, Neil M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Arachidonic acid Autopsy Biological and medical sciences Cause of Death Chromatography, Gas Depression Depressive Disorder, Major - diagnosis docosahexaenoic acid (DHA) Docosahexaenoic Acids - analysis fatty acid Fatty Acids - analysis Female Frontal Lobe - chemistry Humans major depressive disorder (MDD) Male Medical sciences Middle Aged Mood disorders oleic acid orbitofrontal cortex postmortem brain prefrontal cortex Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Sex Factors
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