Gastrointestinal Histoplasmosis in Patients with AIDS: Case Report and Review
Histoplasmosis is the most common endemic mycosis in individuals with AIDS, occurring in 2%–5% of this population. Infection is more likely to be disseminated than in immunocompetent individuals and generally presents insidiously with nonspecific symptoms. The gastrointestinal tract is involved in 7...
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| Veröffentlicht in: | Clinical infectious diseases 2001-02, Vol.32 (3), p.483-491 |
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| container_title | Clinical infectious diseases |
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| creator | Suh, Kathryn N. Anekthananon, Thanomsak Mariuz, Peter R. |
| description | Histoplasmosis is the most common endemic mycosis in individuals with AIDS, occurring in 2%–5% of this population. Infection is more likely to be disseminated than in immunocompetent individuals and generally presents insidiously with nonspecific symptoms. The gastrointestinal tract is involved in 70%–90% of cases of disseminated histoplasmosis, yet gastrointestinal histoplasmosis per se is infrequently encountered in patients with AIDS. The diagnosis of gastrointestinal histoplasmosis is often not suspected, particularly in areas of nonendemicity, and a delay in diagnosis may lead to increased morbidity and risk of death. Since antifungal therapy improves outcome for >80% of AIDS patients with histoplasmosis, it is essential that caregivers be aware of the varied presentations of gastrointestinal histoplasmosis in order to diagnose and to treat this potentially life-threatening infection effectively. |
| doi_str_mv | 10.1086/318485 |
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Infection is more likely to be disseminated than in immunocompetent individuals and generally presents insidiously with nonspecific symptoms. The gastrointestinal tract is involved in 70%–90% of cases of disseminated histoplasmosis, yet gastrointestinal histoplasmosis per se is infrequently encountered in patients with AIDS. The diagnosis of gastrointestinal histoplasmosis is often not suspected, particularly in areas of nonendemicity, and a delay in diagnosis may lead to increased morbidity and risk of death. Since antifungal therapy improves outcome for >80% of AIDS patients with histoplasmosis, it is essential that caregivers be aware of the varied presentations of gastrointestinal histoplasmosis in order to diagnose and to treat this potentially life-threatening infection effectively.</description><identifier>ISSN: 1058-4838</identifier><identifier>EISSN: 1537-6591</identifier><identifier>DOI: 10.1086/318485</identifier><identifier>PMID: 11170958</identifier><identifier>CODEN: CIDIEL</identifier><language>eng</language><publisher>Chicago, IL: The University of Chicago Press</publisher><subject>Abdominal pain ; Adult ; AIDS ; AIDS-Related Opportunistic Infections - diagnosis ; AIDS-Related Opportunistic Infections - drug therapy ; Biological and medical sciences ; Colonoscopy ; Diarrhea ; Fever ; Gastrointestinal Diseases - diagnosis ; Gastrointestinal Diseases - drug therapy ; Gastrointestinal Diseases - microbiology ; Histoplasmosis ; Histoplasmosis - diagnosis ; Histoplasmosis - drug therapy ; HIV Infections - complications ; HIV/AIDS ; Human immunodeficiency virus ; Human viral diseases ; Humans ; Infectious diseases ; Laparotomy ; Male ; Mass ; Medical sciences ; Specimens ; Symptoms ; Tomography, X-Ray Computed ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. 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Infection is more likely to be disseminated than in immunocompetent individuals and generally presents insidiously with nonspecific symptoms. The gastrointestinal tract is involved in 70%–90% of cases of disseminated histoplasmosis, yet gastrointestinal histoplasmosis per se is infrequently encountered in patients with AIDS. The diagnosis of gastrointestinal histoplasmosis is often not suspected, particularly in areas of nonendemicity, and a delay in diagnosis may lead to increased morbidity and risk of death. Since antifungal therapy improves outcome for >80% of AIDS patients with histoplasmosis, it is essential that caregivers be aware of the varied presentations of gastrointestinal histoplasmosis in order to diagnose and to treat this potentially life-threatening infection effectively.</description><subject>Abdominal pain</subject><subject>Adult</subject><subject>AIDS</subject><subject>AIDS-Related Opportunistic Infections - diagnosis</subject><subject>AIDS-Related Opportunistic Infections - drug therapy</subject><subject>Biological and medical sciences</subject><subject>Colonoscopy</subject><subject>Diarrhea</subject><subject>Fever</subject><subject>Gastrointestinal Diseases - diagnosis</subject><subject>Gastrointestinal Diseases - drug therapy</subject><subject>Gastrointestinal Diseases - microbiology</subject><subject>Histoplasmosis</subject><subject>Histoplasmosis - diagnosis</subject><subject>Histoplasmosis - drug therapy</subject><subject>HIV Infections - complications</subject><subject>HIV/AIDS</subject><subject>Human immunodeficiency virus</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Laparotomy</subject><subject>Male</subject><subject>Mass</subject><subject>Medical sciences</subject><subject>Specimens</subject><subject>Symptoms</subject><subject>Tomography, X-Ray Computed</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. Aids</subject><subject>Weight loss</subject><issn>1058-4838</issn><issn>1537-6591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0V9LHDEQAPBQWqq19hNI2VLo29bM5s9k-yZn6wmnLbWF4kvI7SYYu7e7Jrmq397IHudT8SUzMD8mwwwh74B-BqrkIQPFlXhBdkEwLKWo4WXOqVAlV0ztkDcxXlMKoKh4TXYAAGkt1C45OzExhcH3ycbke9MVcx_TMHYmroboY-H74odJ3vYpFrc-XRVHp8cXX4qZibb4acchpML0bU7_eXv7lrxypot2fxP3yO9vX3_N5uXi-8np7GhRNlxAKq0SqpVKSOMoXdaNWULNJSI6dC2i4oZxWhmUjLXAAVqaH9k652TjsK3YHvk09R3DcLPOk-uVj43tOtPbYR01UllVFYpnIWANklXwBJswxBis02PwKxPuNVD9uGE9bTjD95uO6-XKtk9ss9IMPm6AiY3pXDB94-PW1Yyi5Fl9mNSwHv__1cFkrvNFwlZxripBH0cup3I-mL3blk34qyUyFHr-51KL87MaL7HWC_YAvu2i0g</recordid><startdate>20010201</startdate><enddate>20010201</enddate><creator>Suh, Kathryn N.</creator><creator>Anekthananon, Thanomsak</creator><creator>Mariuz, Peter R.</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20010201</creationdate><title>Gastrointestinal Histoplasmosis in Patients with AIDS: Case Report and Review</title><author>Suh, Kathryn N. ; Anekthananon, Thanomsak ; Mariuz, Peter R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c451t-e858d6856af00b9cab1946777f7fd7784a3402a7633d1411d04116dfff6cf7d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Abdominal pain</topic><topic>Adult</topic><topic>AIDS</topic><topic>AIDS-Related Opportunistic Infections - diagnosis</topic><topic>AIDS-Related Opportunistic Infections - drug therapy</topic><topic>Biological and medical sciences</topic><topic>Colonoscopy</topic><topic>Diarrhea</topic><topic>Fever</topic><topic>Gastrointestinal Diseases - diagnosis</topic><topic>Gastrointestinal Diseases - drug therapy</topic><topic>Gastrointestinal Diseases - microbiology</topic><topic>Histoplasmosis</topic><topic>Histoplasmosis - diagnosis</topic><topic>Histoplasmosis - drug therapy</topic><topic>HIV Infections - complications</topic><topic>HIV/AIDS</topic><topic>Human immunodeficiency virus</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Laparotomy</topic><topic>Male</topic><topic>Mass</topic><topic>Medical sciences</topic><topic>Specimens</topic><topic>Symptoms</topic><topic>Tomography, X-Ray Computed</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. Aids</topic><topic>Weight loss</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Suh, Kathryn N.</creatorcontrib><creatorcontrib>Anekthananon, Thanomsak</creatorcontrib><creatorcontrib>Mariuz, Peter R.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Suh, Kathryn N.</au><au>Anekthananon, Thanomsak</au><au>Mariuz, Peter R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gastrointestinal Histoplasmosis in Patients with AIDS: Case Report and Review</atitle><jtitle>Clinical infectious diseases</jtitle><stitle>Clinical Infectious Diseases</stitle><addtitle>Clinical Infectious Diseases</addtitle><date>2001-02-01</date><risdate>2001</risdate><volume>32</volume><issue>3</issue><spage>483</spage><epage>491</epage><pages>483-491</pages><issn>1058-4838</issn><eissn>1537-6591</eissn><coden>CIDIEL</coden><abstract>Histoplasmosis is the most common endemic mycosis in individuals with AIDS, occurring in 2%–5% of this population. Infection is more likely to be disseminated than in immunocompetent individuals and generally presents insidiously with nonspecific symptoms. The gastrointestinal tract is involved in 70%–90% of cases of disseminated histoplasmosis, yet gastrointestinal histoplasmosis per se is infrequently encountered in patients with AIDS. The diagnosis of gastrointestinal histoplasmosis is often not suspected, particularly in areas of nonendemicity, and a delay in diagnosis may lead to increased morbidity and risk of death. Since antifungal therapy improves outcome for >80% of AIDS patients with histoplasmosis, it is essential that caregivers be aware of the varied presentations of gastrointestinal histoplasmosis in order to diagnose and to treat this potentially life-threatening infection effectively.</abstract><cop>Chicago, IL</cop><pub>The University of Chicago Press</pub><pmid>11170958</pmid><doi>10.1086/318485</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| source | Jstor Complete Legacy; Oxford University Press Journals All Titles (1996-Current); MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Abdominal pain Adult AIDS AIDS-Related Opportunistic Infections - diagnosis AIDS-Related Opportunistic Infections - drug therapy Biological and medical sciences Colonoscopy Diarrhea Fever Gastrointestinal Diseases - diagnosis Gastrointestinal Diseases - drug therapy Gastrointestinal Diseases - microbiology Histoplasmosis Histoplasmosis - diagnosis Histoplasmosis - drug therapy HIV Infections - complications HIV/AIDS Human immunodeficiency virus Human viral diseases Humans Infectious diseases Laparotomy Male Mass Medical sciences Specimens Symptoms Tomography, X-Ray Computed Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Weight loss |
| title | Gastrointestinal Histoplasmosis in Patients with AIDS: Case Report and Review |
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