Regulation of mitogen-activated protein kinase pathways by the plasma membrane Na +/H + exchanger, NHE1

The mitogen-activated protein kinases (MAPKs), including extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38 MAPK, play a major role in the regulation of pivotal cellular processes such as cell death/survival balance, cell cycle progression, and cell migration. MAPK a...

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Veröffentlicht in:	Archives of biochemistry and biophysics 2007-06, Vol.462 (2), p.195-201
Hauptverfasser:	Pedersen, Stine Falsig, Darborg, Barbara Vasek, Rentsch, Maria Louise, Rasmussen, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Membrane - metabolism Cell volume regulation ERK Extracellular Signal-Regulated MAP Kinases - metabolism Hypertrophy Intracellular pH Intracellular sodium concentration Ischemia JNK MAP Kinase Signaling System - physiology Models, Biological Osmotic stress p38 MAPK Scaffold Sodium-Hydrogen Exchangers - metabolism
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