Chronic humoral rejection : Identification of antibody-mediated chronic renal allograft rejection by C4d deposits in peritubular capillaries

The pathogenesis of chronic renal allograft rejection (CR) remains obscure. The hypothesis that a subset of CR is mediated by antidonor antibody was tested by determining whether C4d is deposited in peritubular capillaries (PTC) and whether it correlates with circulating antidonor antibodies. All ca...

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Veröffentlicht in:	Journal of the American Society of Nephrology 2001-03, Vol.12 (3), p.574-582
Hauptverfasser:	MAUIYYEDI, Shamila, DELLA PELLE, Patricia, SAIDMAN, Susan, COLLINS, A. Bernard, PASCUAL, Manuel, TOLKOFF-RUBIN, Nina E, WILLIAMS, Winfred W, COSIMI, A. Benedict, SCHNEEBERGER, Eveline E, COLVIN, Robert B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Capillaries - immunology Capillaries - pathology Case-Control Studies Chronic Disease Complement C4 - metabolism Complement C4b Graft Rejection - etiology Graft Rejection - immunology Graft Rejection - pathology HLA Antigens Humans Isoantibodies - blood Kidney Transplantation - adverse effects Kidney Transplantation - immunology Kidney Transplantation - pathology Kidney Tubules - blood supply Medical sciences Microscopy, Fluorescence Middle Aged Peptide Fragments - metabolism Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Tissue Donors
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