light-dependent regulator velvet A of Aspergillus nidulans acts as a repressor of the penicillin biosynthesis

The biosynthesis of the β-lactam antibiotic penicillin in Aspergillus nidulans is catalysed by three enzymes that are encoded by the genes acvA, ipnA and aatA. Several studies have indicated that these genes are controlled by a complex regulatory network, including a variety of cis-acting DNA elemen...

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Veröffentlicht in:	Archives of microbiology 2007-07, Vol.188 (1), p.69-79
Hauptverfasser:	Spröte, Petra, Brakhage, Axel A
Format:	Artikel
Sprache:	eng
Schlagworte:	acvA gene Aspergillus nidulans Aspergillus nidulans - genetics Aspergillus nidulans - metabolism Aspergillus nidulans - radiation effects Aspergillus nidulellus Biological and medical sciences Biosynthesis Blotting, Southern Enzymes Fundamental and applied biological sciences. Psychology Fungal Proteins - genetics Fungal Proteins - metabolism Gene Expression Regulation, Fungal - radiation effects Genes Genes, Fungal - genetics Genes, Fungal - physiology Genes, Regulator - genetics Genes, Regulator - physiology Light Microbiology Miscellaneous Mycology Penicillin biosynthesis Penicillins - biosynthesis Polymerase Chain Reaction Velvet A
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