Immunogenicity of Plasmodium vivax combination subunit vaccine formulated with human compatible adjuvants in mice

Abstract An effective malaria vaccine will probably require the delivery of multiple antigens that induce several layers of immunity. Malaria antigens expressed on the surface and in apical organelles of blood-stage merozoites are potential vaccine candidates given their importance in the invasion o...

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Veröffentlicht in:	Vaccine 2007-07, Vol.25 (28), p.5166-5174
Hauptverfasser:	Devi, Yengkhom Sangeeta, Mukherjee, Paushali, Yazdani, Syed Shams, Shakri, Ahmad Rushdi, Mazumdar, Suman, Pandey, Sunita, Chitnis, Chetan E, Chauhan, Virander S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - administration & dosage Allergy and Immunology Animals Antibodies, Protozoan - blood Antibody Formation - immunology Antigens, Protozoan - genetics Antigens, Protozoan - immunology Applied microbiology Biological and medical sciences Blotting, Western Chromatography, High Pressure Liquid Enzyme-Linked Immunosorbent Assay Fundamental and applied biological sciences. Psychology Human protozoal diseases Humoral response Immunization - methods Immunoglobulin G - blood Infectious diseases Malaria Malaria vaccine Malaria Vaccines - administration & dosage Malaria Vaccines - immunology Malaria, Vivax - immunology Malaria, Vivax - prevention & control Male Medical sciences Merozoite Surface Protein 1 - genetics Merozoite Surface Protein 1 - immunology Mice Mice, Inbred BALB C Microbiology Parasitic diseases Plasmodium vivax Plasmodium vivax - genetics Plasmodium vivax - immunology Protozoal diseases Protozoan Proteins - genetics Protozoan Proteins - immunology Receptors, Cell Surface - genetics Receptors, Cell Surface - immunology Recombinant Proteins - immunology Time Factors Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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