Development of a Catalytic Aromatic Decarboxylation Reaction

A palladium-catalyzed aromatic decarboxylation reaction has been developed. With electron-rich aromatic acids, the reaction proceeds efficiently under fairly mild conditions in good yields. The method was useful with complex functionalized substrates containing hindered carboxylic acids.

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Veröffentlicht in:Organic letters 2007-06, Vol.9 (13), p.2441-2444
Hauptverfasser: Dickstein, Joshua S, Mulrooney, Carol A, O'Brien, Erin M, Morgan, Barbara J, Kozlowski, Marisa C
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Sprache:eng
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