T-cell cytokines affect mucosal immunoglobulin A transport

Abstract Background Secretory immunoglobulin A (sIgA) is the principle immune defense against bacteria and other pathogens in the gut and other mucosal surfaces. sIgA is produced locally by plasma cells and transported (transcytosis) across epithelial cells into luminal secretions. sIgA production a...

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Veröffentlicht in:	The American journal of surgery 2007-07, Vol.194 (1), p.128-133
Hauptverfasser:	Amin, Parth B., M.D, Diebel, Lawrence N., M.D, Liberati, David M., M.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial diseases Bacterial sepsis Biological and medical sciences Biological Transport Enzymes General aspects Glucose HT-29 HT29 Cells Human bacterial diseases Humans IgA transport Immune system Immunoglobulin A - immunology Infectious diseases Interferon-gamma - immunology Interleukin-4 - immunology Intestinal Mucosa - metabolism Lymphocytes Medical sciences pIgR Rodents Sepsis Shock Small intestine Surgery Th1 Cells - immunology Th2 Cells - immunology
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