Effect of a global regulatory gene, afsR2, from Streptomyces lividans on avermectin production in Streptomyces avermitilis

The global regulatory gene, afsR2, from Streptomyces lividans was previously reported to highly stimulate two structurally unrelated antibiotics, actinorhodin and undecylprodigiosin, in both S. lividans and its close relative S. coelicolor. Production of eight avermectin components was also improved...

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Veröffentlicht in:	Journal of bioscience and bioengineering 2000-06, Vol.89 (6), p.606-608
Hauptverfasser:	Lee, Jae-Young, Hwang, Yong-Soon, Kim, Sang-Soo, Kim, Eung-Soo, Choi, Cha-Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	actinorhodin afsR2 afsR2 gene Antibiotics avermectin AVERMECTINS Biological and medical sciences Biosynthesis Biotechnology DNA sequences Fundamental and applied biological sciences. Psychology GENES global regulatory gene Health. Pharmaceutical industry High performance liquid chromatography Industrial applications and implications. Economical aspects Metabolites Microorganisms Production of active biomolecules STREPTOMYCES Streptomyces avermitilis Streptomyces lividans undecylprodigiosin
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